Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 4/20 | 0.39 |
| ▸ | PDGFRA | P16234 | 4/20 | 0.39 |
| ▸ | AHR | P35869 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | TDO2 | P48775 | 1/20 | 0.34 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 5/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.33 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.33 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.33 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 2/20 | 0.33 |
| ▸ | ERN1 | O75460 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25524007 | 0.87 | PDGFRB (0.40) | PDGFRBPDGFRAKDM4EIDO1TDO2 | |
| SCHEMBL31538928 | 0.81 | PDGFRB (0.51) | PDGFRBPDGFRAAHRKDM4EMAP4K4 | |
| SCHEMBL25521682 | 0.81 | PDGFRB (0.51) | PDGFRBPDGFRAAHRKDM4EMAP4K4 | |
| SCHEMBL30873746 | 0.78 | KDM4E (0.56) | PDGFRBPDGFRAKDM4EIDO1TDO2 | |
| SCHEMBL28723760 | 0.78 | KDM4E (0.56) | PDGFRBPDGFRAKDM4EIDO1TDO2 | |
| SCHEMBL25523416 | 0.72 | PDGFRB (0.43) | PDGFRBPDGFRAKDM4EMAP4K4CLK4 | |
| SCHEMBL25521555 | 0.72 | ERN1 (0.50) | KDM4EERN1CA1CA2TP53 | |
| SCHEMBL5215594 | 0.71 | KDM4E (0.53) | KDM4EIDO1TDO2ERN1ALDH1A1 | |
| SCHEMBL25521680 | 0.71 | ADORA2A (0.54) | AHREGFRPIK3CDPIK3CAPIK3CB | |
| SCHEMBL29696057 | 0.70 | ERN1 (0.42) | PDGFRBPDGFRAKDM4EIDO1TDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023086428-A2 | NOVEL MODULATORS OF THE ARYL HYDROCARBON RECEPTOR AND METHODS OF USE THEREOF | ALLIANTHERA (SUZHOU) BIOPHARMACEUTICAL CO., LTD. (CN) | 2023-05-19 | — | — | WO | disclosed |