Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 4/20 | 0.40 |
| ▸ | PDGFRA | P16234 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | TDO2 | P48775 | 1/20 | 0.35 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 5/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.34 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.34 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.34 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.34 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 2/20 | 0.33 |
| ▸ | ERN1 | O75460 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.33 |
| ▸ | MTOR | P42345 | 2/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.33 |
| ▸ | MDM4 | O15151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25523536 | 0.87 | PDGFRB (0.39) | PDGFRBPDGFRAKDM4EIDO1TDO2 | |
| SCHEMBL25524104 | 0.82 | PDGFRB (0.51) | PDGFRBPDGFRAKDM4EMAP4K4CSNK1G2 | |
| SCHEMBL25521916 | 0.79 | ERN1 (0.46) | MAPK10ERN1CA1CA2CA9 | |
| SCHEMBL30873746 | 0.79 | KDM4E (0.56) | PDGFRBPDGFRAKDM4EIDO1TDO2 | |
| SCHEMBL28723760 | 0.79 | KDM4E (0.56) | PDGFRBPDGFRAKDM4EIDO1TDO2 | |
| SCHEMBL25522058 | 0.77 | ADORA2A (0.50) | ERN1PIK3CDPIK3CAPIK3CBMTOR | |
| SCHEMBL25523900 | 0.75 | RAF1 (0.39) | PDGFRBPDGFRAMAPK10CLK4PIK3CA | |
| SCHEMBL25522059 | 0.75 | MAP4K4 (0.54) | MAP4K4 | |
| SCHEMBL25523902 | 0.74 | TNIK (0.45) | PDGFRBPDGFRAMAP4K4CLK4EGFR | |
| SCHEMBL25522194 | 0.74 | AR (0.50) | KDM4EIDO1TDO2ALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023086428-A2 | NOVEL MODULATORS OF THE ARYL HYDROCARBON RECEPTOR AND METHODS OF USE THEREOF | ALLIANTHERA (SUZHOU) BIOPHARMACEUTICAL CO., LTD. (CN) | 2023-05-19 | — | — | WO | disclosed |