Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.51 |
| ▸ | TLR8 | Q9NR97 | 6/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | BACE1 | P56817 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20855335 | 0.98 | TLR8 (0.51) | CYP1A2PDE10ATLR8KDM4EBACE1 | |
| SCHEMBL8671753 | 0.95 | CYP1A2 (0.53) | CYP1A2PDE10ATLR8KDM4EBACE1 | |
| SCHEMBL13777688 | 0.88 | KDM4E (0.62) | CYP1A2PDE10AKDM4EBACE1SMN1; SMN2 | |
| SCHEMBL8125167 | 0.84 | CYP1A2 (0.51) | CYP1A2PDE10AKDM4EBACE1KMT2A | |
| SCHEMBL23044015 | 0.83 | TLR8 (0.52) | TLR8KDM4EMEN1KMT2AATM | |
| SCHEMBL6239656 | 0.83 | KDM4E (0.52) | TLR8KDM4EMEN1KMT2AKCNH2 | |
| SCHEMBL7039076 | 0.83 | KDM4E (0.49) | TLR8KDM4EMEN1KMT2AKCNH2 | |
| SCHEMBL16431372 | 0.81 | KDM4E (0.54) | TLR8KDM4EMEN1KMT2AKCNH2 | |
| SCHEMBL16432811 | 0.81 | KDM4E (0.54) | TLR8KDM4EMEN1KMT2AKCNH2 | |
| SCHEMBL170164 | 0.81 | KDM4E (0.54) | TLR8KDM4EMEN1KMT2AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105820117-B | The preparation method of 2- aryl -4- methylquinoline compounds | 浙江大学 | 2018-05-29 | — | — | CN | claimed |
| WO-2023077218-A1 | PHOTOCATALYSTS, PREPARATION AND USE THEREOF | THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING / MCGILL UNIVERSITY (CA) | 2023-05-11 | — | — | WO | disclosed |
| CN-112939857-A | Synthetic method of alkylated quinoline compound | 中国科学院大连化学物理研究所 | 2021-06-11 | — | — | CN | disclosed |
| CN-105820117-B | The preparation method of 2- aryl -4- methylquinoline compounds | 浙江大学 | 2018-05-29 | — | — | CN | disclosed |
| CN-105820117-A | Method for preparing 2-aryl-4-methyl quinoline compound | 浙江大学 | 2016-08-03 | — | — | CN | disclosed |