SCHEMBL170164

SCHEMBL170164

CCCCCCCc1cc(O)c2ccccc2n1

nearest known ligand 0.54

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.54
ALDH1A1 P00352 3/20 0.54
GAA P10253 2/20 0.54
HPGD P15428 2/20 0.54
USP2 O75604 1/20 0.54
GLA P06280 1/20 0.54
CYP3A4 P08684 1/20 0.54
MAPT P10636 1/20 0.54
CASP1 P29466 1/20 0.54
CASP7 P55210 1/20 0.54
HSD17B10 Q99714 1/20 0.54
KCNH2 Q12809 1/20 0.49
TLR8 Q9NR97 4/20 0.47
LMNA P02545 1/20 0.47
TSHR P16473 1/20 0.47
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
ATM Q13315 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16431614 1.00 KDM4E (0.54) KDM4EALDH1A1GAAHPGDUSP2
SCHEMBL16431209 1.00 KDM4E (0.54) KDM4EALDH1A1GAAHPGDUSP2
SCHEMBL29368070 1.00 KDM4E (0.54) KDM4EALDH1A1GAAHPGDUSP2
SCHEMBL16431027 1.00 KDM4E (0.54) KDM4EALDH1A1GAAHPGDUSP2
SCHEMBL16431372 1.00 KDM4E (0.54) KDM4EALDH1A1GAAHPGDUSP2
SCHEMBL2126335 1.00 KDM4E (0.54) KDM4EALDH1A1GAAHPGDUSP2
SCHEMBL16433240 1.00 KDM4E (0.54) KDM4EALDH1A1GAAHPGDUSP2
SCHEMBL16432811 1.00 KDM4E (0.54) KDM4EALDH1A1GAAHPGDUSP2
Methane SCHEMBL28127790 0.98 KDM4E (0.53) KDM4EALDH1A1GAAHPGDUSP2
SCHEMBL6239656 0.98 KDM4E (0.52) KDM4EALDH1A1GAAHPGDUSP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 225 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4702981-A1 TARGETED ANTIBACTERIAL TREATMENT Københavns Universitet (DK) 2026-03-04 EP claimed
CN-106434785-B The preparation method of 2-n- heptyl -4- oxyquinoline 遵义医科大学 2019-08-06 CN claimed
CN-106434785-A Preparation method of 2-n-heptyl-4-hydroxyquinoline 遵义医学院 2017-02-22 CN claimed
US-9170250-B2 Oilfield chemicals with attached spin probes BAKER HUGHES INCORPORATED (US) 2015-10-27 US claimed
US-8906602-B2 Methods for identifying candidate compounds for treating, reducing, or preventing pathogenic infections THE GENERAL HOSPITAL CORPORATION (US) 2014-12-09 US claimed
EP-2598651-A1 METHODS AND USES RELATING TO THE IDENTIFICATION OF COMPOUND ASSOCIATED WITH BACTERIAL INFECTION Sanofi-Aventis Deutschland GmbH (DE) 2013-06-05 EP claimed
US-20130123360-A1 METHODS AND USES RELATING TO THE IDENTIFICATION OF COMPOUND ASSOCIATED WITH BACTERIAL INFECTION SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) 2013-05-16 US claimed
WO-2012013621-A1 METHODS AND USES RELATING TO THE IDENTIFICATION OF COMPOUND ASSOCIATED WITH BACTERIAL INFECTION SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) 2012-02-02 WO claimed
EP-2412819-A1 Methods and uses relating to the identification of compound associated with bacterial infection Sanofi-Aventis Deutschland GmbH (DE) 2012-02-01 EP claimed
US-20070292851-A1 Methods for Identifying Candidate Compounds for Treating, Reducing, or Preventing Pathogenic Infections THE GENERAL HOSPITAL CORPORATION 2007-12-20 US claimed
US-20070099889-A1 Use of pseudan and pseudan inclusion bodies GEORGE MASON INTELLECTUAL PROPERTIES, INC. 2007-05-03 US claimed
WO-2007008769-A2 USE OF PSEUDAN AND PSEUDAN INCLUSION BODIES GEORGE MASON UNIVERSITY (US) 2007-01-18 WO claimed
WO-2005069989-A2 METHODS FOR IDENTIFYING CANDIDATE COMPOUNDS FOR TREATING, REDUCING, OR PREVENTING PATHOGENIC INFECTIONS THE GENERAL HOSPITAL CORPORATION (US) 2005-08-04 WO claimed
EP-3487495-B1 4-(4-CHLOROPHENYL)-5-METHYLENE-PYRROL-2-ONE OR 5- METHYLENE-4-(P-TOLYL)PYRROL-2-ONE FOR USE IN THE TREATMENT OF A BACTERIAL SKIN LESIONS UNILEVER IP HOLDINGS B V (NL) 2026-04-22 EP disclosed
EP-3487496-B1 4-(4-CHLOROPHENYL)-5-METHYLENE-PYRROL-2-ONE AND 5-METHYLENE-4-(P-TOLYL)PYRROL-2-ONE FOR USE IN THE TREATMENT OF GRAM NEGATIVE BACTERIAL INFECTIONS UNILEVER IP HOLDINGS B V (NL) 2026-04-08 EP disclosed
EP-3487494-B1 4-(4-CHLOROPHENYL)-5-METHYLENE-PYRROL-2-ONE OR 5-METHYLENE-4-(P-TOLYL)PYRROL-2-ONE FOR USE IN THE TREATMENT OF BACTERIAL RESPIRATORY TRACT INFECTION UNILEVER IP HOLDINGS B V (NL) 2026-03-25 EP disclosed
WO-2003041709-A1 COMPOSITIONS AND METHODS OF TREATING IRON EXCESS GEORGE MASON UNIVERSITY (US) 2003-05-22 WO disclosed
WO-2003037259-A2 METHODS FOR THE PREVENTION OR TREATMENT OF BACTERIAL AND FUNGAL INFECTIONS THE GENERAL HOSPITAL CORPORATION (US) 2003-05-08 WO disclosed
WO-1995028929-A1 AMINOLINE-N-OXIDE ANTIMICROBIALS FOR USE AGAINST H. PYLORI INFECTIONS RPMS TECHNOLOGY LIMITED (GB) 1995-11-02 WO disclosed
WO-1995028929-A1 AMINOLINE-N-OXIDE ANTIMICROBIALS FOR USE AGAINST H. PYLORI INFECTIONS RPMS TECHNOLOGY LIMITED (GB) 1995-11-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070099889-A1 Use of pseudan and pseudan inclusion bodies MMP8, ETF1, MMP1 KDM4E 3129/4885ALDH1A1 3910/4885GAA 458/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.