Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 5/20 | 0.43 |
| ▸ | CA1 | P00915 | 3/20 | 0.42 |
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA7 | P43166 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13027131 | 0.81 | SMN1; SMN2 (0.47) | SMN1; SMN2KDM4EHSD17B10TP53MAPT | |
| SCHEMBL10356448 | 0.81 | SMN1; SMN2 (0.47) | SMN1; SMN2KDM4EHSD17B10TP53MAPT | |
| SCHEMBL31443869 | 0.81 | SMN1; SMN2 (0.47) | SMN1; SMN2KDM4EHSD17B10TP53MAPT | |
| SCHEMBL2551189 | 0.80 | CA1 (0.55) | SMN1; SMN2KDM4EHSD17B10TP53MAPT | |
| SCHEMBL29178172 | 0.79 | SMN1; SMN2 (0.45) | SMN1; SMN2KDM4EHSD17B10TP53MAPT | |
| SCHEMBL30738330 | 0.79 | SMN1; SMN2 (0.45) | SMN1; SMN2KDM4EHSD17B10TP53MAPT | |
| SCHEMBL12816517 | 0.79 | SMN1; SMN2 (0.45) | SMN1; SMN2KDM4EHSD17B10TP53MAPT | |
| SCHEMBL16167542 | 0.78 | SMN1; SMN2 (0.44) | SMN1; SMN2KDM4EHSD17B10TP53MAPT | |
| SCHEMBL25434306 | 0.77 | CA1 (0.61) | SMN1; SMN2KDM4EHSD17B10TP53MAPT | |
| SCHEMBL151213 | 0.77 | CA1 (0.61) | SMN1; SMN2KDM4EHSD17B10TP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2556078-B1 | CATALYSTS FOR ALKYNE METATHESIS | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2014-09-24 | — | — | EP | disclosed |
| EP-2556078-A1 | CATALYSTS FOR ALKYNE METATHESIS | Studiengesellschaft Kohle MbH (DE) | 2013-02-13 | — | — | EP | disclosed |
| WO-2011120508-A1 | CATALYSTS FOR ALKYNE METATHESIS | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2011-10-06 | — | — | WO | disclosed |