SCHEMBL29178172

SCHEMBL29178172

COc1cccc([Si](OC)(OC)c2cccc(OC)c2OC)c1OC

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.45
CA12 O43570 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
CA4 P22748 1/20 0.42
CA7 P43166 1/20 0.42
CA9 Q16790 1/20 0.42
CA14 Q9ULX7 1/20 0.42
NFE2L2 Q16236 5/20 0.41
HSD17B10 Q99714 3/20 0.40
KDM4E B2RXH2 2/20 0.40
MAPT P10636 2/20 0.40
MGAM O43451 1/20 0.40
GAA P10253 1/20 0.40
SI P14410 1/20 0.40
MGAM2 Q2M2H8 1/20 0.40
ALDH1A1 P00352 1/20 0.39
LMNA P02545 1/20 0.39
TP53 P04637 1/20 0.39
CYP3A4 P08684 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30738330 1.00 SMN1; SMN2 (0.45) SMN1; SMN2CA12CA1CA2CA4
SCHEMBL13027131 0.85 SMN1; SMN2 (0.47) SMN1; SMN2CA12CA1CA2CA4
SCHEMBL29033101 0.81 SMN1; SMN2 (0.44) SMN1; SMN2CA12CA1CA2CA4
SCHEMBL10356448 0.81 SMN1; SMN2 (0.47) SMN1; SMN2CA12CA1CA2CA4
SCHEMBL31443869 0.81 SMN1; SMN2 (0.47) SMN1; SMN2CA12CA1CA2CA4
SCHEMBL12816517 0.79 SMN1; SMN2 (0.45) SMN1; SMN2CA12CA1CA2CA4
SCHEMBL2552363 0.79 SMN1; SMN2 (0.45) SMN1; SMN2CA12CA1CA2CA4
SCHEMBL16167542 0.78 SMN1; SMN2 (0.44) SMN1; SMN2CA12CA1CA2CA4
SCHEMBL25434306 0.77 CA1 (0.61) SMN1; SMN2CA12CA1CA2CA4
SCHEMBL151213 0.77 CA1 (0.61) SMN1; SMN2CA12CA1CA2CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114381156-B Metal oxide dispersion composition, method for producing same, film composition containing same, optical film, and optical element 凯斯科技股份有限公司 2024-03-12 CN claimed
CN-115710438-B Metal oxide dispersion, thin film composition for display, and optical element for display 凯斯科技股份有限公司 2024-01-30 CN disclosed