Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 5/20 | 0.57 |
| ▸ | CA1 | P00915 | 5/20 | 0.57 |
| ▸ | CA2 | P00918 | 5/20 | 0.57 |
| ▸ | CA9 | Q16790 | 5/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | TYMP | P19971 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 8/20 | 0.37 |
| ▸ | NOS1 | P29475 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11390072 | 0.89 | CA12 (0.64) | CA12CA1CA2CA9LMNA | |
| SCHEMBL8431954 | 0.86 | CA12 (0.61) | CA12CA1CA2CA9LMNA | |
| Hydrochloric Acid SCHEMBL12004636 | 0.84 | CA12 (0.60) | CA12CA1CA2CA9LMNA | |
| SCHEMBL4360078 | 0.83 | CA12 (0.58) | CA12CA1CA2CA9LMNA | |
| SCHEMBL11111165 | 0.82 | CA12 (0.57) | CA12CA1CA2CA9LMNA | |
| SCHEMBL920293 | 0.82 | LMNA (0.60) | CA12CA1CA2CA9LMNA | |
| SCHEMBL11108846 | 0.82 | CA12 (0.57) | CA12CA1CA2CA9LMNA | |
| SCHEMBL13942803 | 0.82 | CA12 (0.57) | CA12CA1CA2CA9LMNA | |
| SCHEMBL4357511 | 0.81 | CA12 (0.57) | CA12CA1CA2CA9LMNA | |
| Hydrochloric Acid SCHEMBL31250585 | 0.81 | CA12 (0.57) | CA12CA1CA2CA9LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130096123-A1 | RADIATION SENSITISER COMPOSITIONS | EUPHARMA PTY LTD (AU) | 2013-04-18 | — | — | US | disclosed |
| EP-2558090-A1 | RADIATION SENSITISER COMPOSITIONS | Eupharma Pty Ltd (AU) | 2013-02-20 | — | — | EP | disclosed |
| CN-102933213-A | Radiation sensitiser compositions | EUPHARMA PTY LTD | 2013-02-13 | — | — | CN | disclosed |
| WO-2011127537-A1 | RADIATION SENSITISER COMPOSITIONS | PHEBRA PTY LTD (AU) | 2011-10-20 | — | — | WO | disclosed |