Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 9/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | QPCT | Q16769 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10768414 | 0.83 | TBXAS1 (0.62) | TBXAS1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL29004413 | 0.80 | TBXAS1 (1.00) | TBXAS1 | |
| SCHEMBL2535103 | 0.80 | TBXAS1 (1.00) | TBXAS1 | |
| SCHEMBL29004411 | 0.80 | TBXAS1 (1.00) | TBXAS1 | |
| SCHEMBL2532389 | 0.80 | TBXAS1 (1.00) | TBXAS1 | |
| SCHEMBL2533366 | 0.80 | TBXAS1 (1.00) | TBXAS1 | |
| SCHEMBL285054 | 0.80 | TBXAS1 (1.00) | TBXAS1 | |
| SCHEMBL10247600 | 0.80 | TBXAS1 (1.00) | TBXAS1 | |
| SCHEMBL939851 | 0.80 | TBXAS1 (1.00) | TBXAS1 | |
| SCHEMBL1679410 | 0.80 | TBXAS1 (1.00) | TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023091726-A1 | INHIBITORS OF CYCLIN‑DEPENDENT KINASE 12 (CDK12) | SYROS PHARMACEUTICALS, INC. (US) | 2023-05-25 | — | — | WO | disclosed |