Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | GRM5 | P41594 | 3/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22326439 | 0.80 | MAPT (0.50) | APPNPSR1GRM5KCNH2NPC1 | |
| SCHEMBL28389232 | 0.73 | NPC1 (0.48) | APPNPSR1GRM5KCNH2NPC1 | |
| SCHEMBL13073860 | 0.73 | CYP2A6 (0.61) | GRM5CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL10699281 | 0.73 | APP (0.48) | APPNPSR1GRM5KCNH2NPC1 | |
| Diphenylacetylene SCHEMBL29188592 | 0.73 | APP (1.00) | APPGRM5KCNH2NPC1MTOR | |
| Diphenylacetylene SCHEMBL68254 | 0.73 | APP (1.00) | APPGRM5KCNH2NPC1MTOR | |
| Diphenylacetylene SCHEMBL960609 | 0.73 | APP (1.00) | APPGRM5KCNH2NPC1MTOR | |
| SCHEMBL497768 | 0.72 | TSHR (0.48) | APPNPSR1GRM5KCNH2NPC1 | |
| SCHEMBL2923198 | 0.72 | APP (0.52) | APPNPSR1GRM5KCNH2NPC1 | |
| SCHEMBL22326436 | 0.72 | APP (0.55) | APPNPSR1KCNH2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117209452-A | Difluoro benzothiadiazole full-color fluorescent molecule, preparation and application thereof | 华南师范大学 | 2023-12-12 | — | — | CN | claimed |
| EP-3601282-B1 | NOVEL PYRIDO[2,3-B]INDOLE COMPOUNDS FOR THE TREATMENT AND PROPHYLAXIS OF BACTERIAL INFECTION | HOFFMANN LA ROCHE (CH) | 2021-07-21 | — | — | EP | claimed |
| EP-1651621-B1 | 2- (QUINOXALIN-5-YLSULFONYLAMINO) -BENZAMIDE COMPOUNDS AS CCK2 MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2008-08-06 | — | — | EP | claimed |
| CN-117209452-A | Difluoro benzothiadiazole full-color fluorescent molecule, preparation and application thereof | 华南师范大学 | 2023-12-12 | — | — | CN | disclosed |
| CN-111073724-B | Lithium-based lubricating grease and preparation method thereof | 中国石油化工股份有限公司 | 2022-08-09 | — | — | CN | disclosed |
| CN-111100158-B | Silole derivative, preparation method and application thereof, and photoluminescent lubricating grease | 中国石油化工股份有限公司 | 2022-07-15 | — | — | CN | disclosed |
| CN-113754603-A | Application of isoxazole compound as viscosity fluorescent probe | 浙江工业大学 | 2021-12-07 | — | — | CN | disclosed |
| CN-111100158-A | Silole derivative, preparation method and application thereof, and photoluminescent lubricating grease | 中国石油化工股份有限公司 | 2020-05-05 | — | — | CN | disclosed |
| CN-111073724-A | Lithium-based lubricating grease and preparation method thereof | 中国石油化工股份有限公司 | 2020-04-28 | — | — | CN | disclosed |
| CN-111073725-A | Photoluminescent grease composition, photoluminescent material and preparation method thereof | 中国石油化工股份有限公司 | 2020-04-28 | — | — | CN | disclosed |
| CN-105793804-A | Method for producing touch sensor member, and touch sensor member | 东丽株式会社 | 2016-07-20 | — | — | CN | disclosed |
| EP-0776893-B1 | Azaheterocyclic compounds having tachykinin receptor antagonist activity; Nk1 and NK2 | SANKYO CO (JP) | 2002-02-27 | — | — | EP | disclosed |
| EP-0834499-B1 | Process for the preparation of aromatic vinyl compounds | DAINIPPON INK & CHEMICALS (JP) | 2001-07-25 | — | — | EP | disclosed |
| US-6159967-A | Heterocyclic compounds having tachykinin receptor antagonist activity their preparation and their use | SANKYO COMPANY, LIMITED (JP) | 2000-12-12 | — | — | US | disclosed |
| EP-0834499-A1 | Process for the preparation of aromatic vinyl compounds | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1998-04-08 | — | — | EP | disclosed |
| WO-1997027049-A1 | HYPERPOLARIZABLE COMPOUNDS AND DEVICES FABRICATED THEREFROM | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 1997-07-31 | — | — | WO | disclosed |
| EP-0776893-A1 | Azaheterocyclic compounds having tachykinin receptor antagonist activity; Nk1 and NK2 | SANKYO COMPANY LIMITED (JP) | 1997-06-04 | — | — | EP | disclosed |
| US-3981893-A | HYPOTENSIVE AGENTS, CARDIOVASCULAR DISORDERS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-09-21 | — | — | US | disclosed |
| US-3974290-A | Vasodilating and antihypertensive compositions and methods of effecting vasodilation and treating hypertension utilizing 2-amino-4H pyrane as the active agent | BAYER AKTIENGESELLSCHAFT (DT) | 1976-08-10 | — | — | US | disclosed |
| US-3966767-A | CORONARY ACTION, ANTI-HYPERTENSIVE AGENTS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-06-29 | — | — | US | disclosed |