Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | GAA | P10253 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | TRPV1 | Q8NER1 | 7/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | PLAU | P00749 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2555605 | 0.98 | KDM4E (0.57) | KDM4EALDH1A1GAAMAPTMEN1 | |
| SCHEMBL2555495 | 0.98 | KDM4E (0.57) | KDM4EALDH1A1GAAMAPTMEN1 | |
| SCHEMBL8655906 | 0.93 | KDM4E (0.62) | KDM4EALDH1A1GAAMAPTMEN1 | |
| SCHEMBL2555596 | 0.84 | KDM4E (0.47) | KDM4EALDH1A1GAAMAPTMEN1 | |
| SCHEMBL28140458 | 0.80 | KDM4E (0.72) | KDM4EALDH1A1GAAMAPTMEN1 | |
| SCHEMBL1566759 | 0.80 | KDM4E (0.62) | KDM4EALDH1A1GAAMAPTMEN1 | |
| Bromide SCHEMBL7030618 | 0.78 | KDM4E (0.60) | KDM4EALDH1A1GAAMAPTMEN1 | |
| Fluoride SCHEMBL7034780 | 0.78 | KDM4E (0.60) | KDM4EALDH1A1GAAMAPTMEN1 | |
| Hydrochloric Acid SCHEMBL7036095 | 0.78 | KDM4E (0.60) | KDM4EALDH1A1GAAMAPTMEN1 | |
| Iodide SCHEMBL7033986 | 0.78 | KDM4E (0.60) | KDM4EALDH1A1GAAMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8999942-B2 | Polyol modified aminoglycoside-lipid conjugates | UNIVERSITY OF MANITOBA (CA) | 2015-04-07 | — | — | US | disclosed |
| US-20130157969-A1 | POLYOL MODIFIED AMINOGLYCOSIDE-LIPID CONJUGATES | UNIVERSITY OF MANITOBA (CA) | 2013-06-20 | — | — | US | disclosed |
| EP-2556079-A2 | POLYOL MODIFIED AMINOGLYCOSIDE-LIPID CONJUGATES | University Of Manitoba (CA) | 2013-02-13 | — | — | EP | disclosed |
| WO-2011124986-A2 | POLYOL MODIFIED AMINOGLYCOSIDE-LIPID CONJUGATES | UNIVERSITY OF MANITOBA (CA) | 2011-10-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130157969-A1 | POLYOL MODIFIED AMINOGLYCOSIDE-LIPID CONJUGATES | AADAC, DDOST, AARS1 | KDM4E 2382/4885ALDH1A1 3346/4885GAA 129/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.