Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KDM4D | Q6B0I6 | 2/20 | 0.37 |
| ▸ | SUV39H2 | Q9H5I1 | 4/20 | 0.36 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.35 |
| ▸ | KAT8 | Q9H7Z6 | 4/20 | 0.35 |
| ▸ | CFTR | P13569 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30397566 | 0.93 | BTK (0.40) | BTKKMT2AL3MBTL1KDM4DSUV39H2 | |
| SCHEMBL25525026 | 0.92 | BTK (0.40) | BTKKMT2AL3MBTL1KDM4DSUV39H2 | |
| SCHEMBL25525729 | 0.91 | BTK (0.43) | BTKKMT2AL3MBTL1KDM4DSUV39H2 | |
| SCHEMBL25524998 | 0.89 | BTK (0.40) | BTKKMT2AL3MBTL1SUV39H2KAT8 | |
| SCHEMBL25525043 | 0.86 | SUV39H2 (0.44) | BTKKMT2AL3MBTL1KDM4DSUV39H2 | |
| SCHEMBL30397473 | 0.85 | BTK (0.40) | BTKKMT2AL3MBTL1KDM4DSUV39H2 | |
| SCHEMBL25525052 | 0.83 | BTK (0.43) | BTKKMT2AL3MBTL1SUV39H2MAPK13 | |
| SCHEMBL25525053 | 0.82 | BTK (0.40) | BTKKMT2AL3MBTL1SUV39H2KAT8 | |
| SCHEMBL25417460 | 0.81 | MAPK13 (0.42) | BTKKMT2AL3MBTL1KDM4DSUV39H2 | |
| SCHEMBL25540956 | 0.81 | BTK (0.42) | BTKKMT2AL3MBTL1MAPK13KAT8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023091726-A1 | INHIBITORS OF CYCLIN‑DEPENDENT KINASE 12 (CDK12) | SYROS PHARMACEUTICALS, INC. (US) | 2023-05-25 | — | — | WO | disclosed |
| WO-2023091726-A1 | INHIBITORS OF CYCLIN‑DEPENDENT KINASE 12 (CDK12) | SYROS PHARMACEUTICALS, INC. (US) | 2023-05-25 | — | — | WO | disclosed |