⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25758622 | 0.85 | — | — | |
| SCHEMBL15044657 | 0.77 | — | — | |
| SCHEMBL255263 | 0.74 | — | — | |
| SCHEMBL13345935 | 0.73 | — | — | |
| SCHEMBL19558702 | 0.71 | — | — | |
| SCHEMBL25758704 | 0.69 | — | — | |
| SCHEMBL6045522 | 0.67 | SMN1; SMN2 (0.34) | — | |
| SCHEMBL6045477 | 0.67 | SMN1; SMN2 (0.34) | — | |
| SCHEMBL25758615 | 0.67 | — | — | |
| Bromoacetal SCHEMBL103234 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2611295-B1 | FUSED TRICYCLIC ETHER CARBAMATES AND THEIR USE | PURDUE RESEARCH FOUNDATION (US) | 2017-07-19 | — | — | EP | disclosed |
| US-9487541-B2 | Fused tricyclic ether carbamates and their use | PURDUE RESEARCH FOUNDATION (US) | 2016-11-08 | — | — | US | disclosed |
| US-20140179754-A1 | FUSED TRICYCLIC ETHER CARBAMATES AND THEIR USE | NATIONAL UNIVERSITY CORPORATION KUMAMOTO UNIVERSITY (JP) | 2014-06-26 | — | — | US | disclosed |
| US-8563597-B2 | Fused tricyclic ether carbamates and their use | PURDUE RESEARCH FOUNDATION (US) | 2013-10-22 | — | — | US | disclosed |
| US-20130158094-A1 | FUSED TRICYCLIC ETHER CARBAMATES AND THEIR USE | PURDUE RESEARCH FOUNDATION (US) | 2013-06-20 | — | — | US | disclosed |
| WO-2012031237-A1 | FUSED TRICYCLIC ETHER CARBAMATES AND THEIR USE | PURDUE RESEARCH FOUNDATION (US) | 2012-03-08 | — | — | WO | disclosed |