⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromoacetal SCHEMBL11383920 | 0.97 | THRB (0.42) | — | |
| SCHEMBL320691 | 0.87 | — | — | |
| SCHEMBL13430505 | 0.85 | — | — | |
| SCHEMBL24176769 | 0.84 | LMNA (0.38) | — | |
| SCHEMBL14433106 | 0.83 | — | — | |
| SCHEMBL24947660 | 0.79 | — | — | |
| SCHEMBL16273246 | 0.77 | — | — | |
| SCHEMBL1297783 | 0.75 | THRB (0.40) | — | |
| SCHEMBL10430663 | 0.75 | CA1 (0.31) | — | |
| SCHEMBL21618241 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 6672 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12428426-B2 | Process and intermediates for preparing a JAK1 inhibitor | INCYTE CORPORATION (US) | 2025-09-30 | — | — | US | claimed |
| CN-120118086-A | 1, 7-Disubstituted pyrrolo [1,2-a ] pyrazine compound and preparation method and application thereof | 沈阳药科大学 | 2025-06-10 | — | — | CN | claimed |
| CN-119968367-A | Novel heterocyclylphenylmethylamine derivatives, process for their preparation and their use for preventing, alleviating or treating multiple sclerosis | 韩国科学技术研究院 | 2025-05-09 | — | — | CN | claimed |
| CN-119930568-A | Galanthamine intermediate compound and its synthesis process | 广东东阳光药业股份有限公司 | 2025-05-06 | — | — | CN | claimed |
| EP-3694864-B1 | BORONIC ACID DERIVATIVES AND SYNTHESIS THEREOF | QPEX BIOPHARMA INC (US) | 2025-03-05 | — | — | EP | claimed |
| CN-119534664-A | Method for detecting genotoxic impurities in tofacitinib citrate starting material by gas-phase mass spectrometry | 江苏正大清江制药有限公司 | 2025-02-28 | — | — | CN | claimed |
| WO-2025038484-A1 | METHOD FOR PREPARING CYCLOHEXYL THIAZOLYL PHENYL CARBAMATE | CYTEIR THERAPEUTICS, INC. (US) | 2025-02-20 | — | — | WO | claimed |
| US-12221427-B2 | Preparation method of (5-fluoro-2,3-dihydrobenzofuran-4-yl)methanamine or its salt, and intermediates thereof | ASCENTAGE PHARMA (SUZHOU) CO., LTD. (CN) | 2025-02-11 | — | — | US | claimed |
| CN-119101047-A | Industrial production process of fibrauretine and its analogues | 四川定科制药有限公司 | 2024-12-10 | — | — | CN | claimed |
| CN-118994193-A | Organic light-heat conversion reagent and preparation method and application thereof | 兰州大学 | 2024-11-22 | — | — | CN | claimed |
| US-6844375-B2 | 4-methylene-1,3-dioxolanes as cross-linking agents | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-01-18 | — | — | US | claimed |
| EP-0470127-B1 | PCP RECEPTOR LIGANDS AND THE USE THEREOF | OREGON STATE (US) | 2003-02-26 | — | — | EP | claimed |
| US-5731435-A | Process for the preparation of heterocyclic alkylamide derivatives | G. D. SEARLE & CO. (US) | 1998-03-24 | — | — | US | claimed |
| EP-0424464-B1 | THERMALLY STABLE PHENOLIC RESIN COMPOSITIONS AND THEIR USE IN LIGHT-SENSITIVE COMPOSITIONS | OCG MICROELECTRONIC MATERIALS (US) | 1994-05-04 | — | — | EP | claimed |
| US-5157153-A | Reacting alkyl ethynyl ether or monohaloacetaldehyde acetal with alkali metal base, then with halodihydrocarbylphosphine; adding mineral acid, hydrolyzing | PHILLIPS PETROLEUM COMPANY (US) | 1992-10-20 | — | — | US | claimed |
| US-5053479-A | A halocetaldehyde source, alone or with a formaldehyde source; a phenolic monomer, solvent; positive-working photoresists | OCG MICROELECTRONIC MATERIALS, INC. (US) | 1991-10-01 | — | — | US | claimed |
| EP-0424464-A4 | THERMALLY STABLE PHENOLIC RESIN COMPOSITIONS AND THEIR USE IN LIGHT-SENSITIVE COMPOSITIONS | — | 1991-09-25 | — | — | EP | claimed |
| EP-0424464-A1 | THERMALLY STABLE PHENOLIC RESIN COMPOSITIONS AND THEIR USE IN LIGHT-SENSITIVE COMPOSITIONS. | OLIN HUNT SPECIALTY PROD (US) | 1991-05-02 | — | — | EP | claimed |
| US-4959292-A | Light-sensitive o-quinone diazide composition and product with phenolic novolak prepared by condensation with haloacetoaldehyde | OLIN HUNT SPECIALTY PRODUCTS INC. (US) | 1990-09-25 | — | — | US | claimed |
| WO-1990000571-A1 | THERMALLY STABLE PHENOLIC RESIN COMPOSITIONS AND THEIR USE IN LIGHT-SENSITIVE COMPOSITIONS | OLIN HUNT SPECIALTY PRODUCTS INC. (US) | 1990-01-25 | — | — | WO | claimed |