Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINA3 | P01011 | 1/20 | 0.52 |
| ▸ | TMIGD3 | P0DMS9 | 3/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 7/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NSD2 | O96028 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.31 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25542572 | 0.93 | SERPINA3 (0.51) | SERPINA3TMIGD3ADORA2AADORA1CYP3A4 | |
| SCHEMBL25542380 | 0.93 | SERPINA3 (0.51) | SERPINA3TMIGD3ADORA2AADORA1CYP3A4 | |
| SCHEMBL25542031 | 0.93 | SERPINA3 (0.51) | SERPINA3TMIGD3ADORA2AADORA1CYP3A4 | |
| SCHEMBL25531012 | 0.93 | SERPINA3 (0.51) | SERPINA3TMIGD3ADORA2AADORA1CYP3A4 | |
| SCHEMBL25527305 | 0.93 | SERPINA3 (0.51) | SERPINA3TMIGD3ADORA2AADORA1CYP3A4 | |
| SCHEMBL25542052 | 0.93 | SERPINA3 (0.51) | SERPINA3TMIGD3ADORA2AADORA1CYP3A4 | |
| SCHEMBL25526907 | 0.92 | SERPINA3 (0.50) | SERPINA3TMIGD3ADORA2AADORA1CYP3A4 | |
| SCHEMBL25526895 | 0.91 | SERPINA3 (0.54) | SERPINA3TMIGD3ADORA2AADORA1CYP3A4 | |
| SCHEMBL25526914 | 0.91 | SERPINA3 (0.54) | SERPINA3TMIGD3ADORA2AADORA1CYP3A4 | |
| SCHEMBL25527477 | 0.89 | SERPINA3 (0.46) | SERPINA3TMIGD3ADORA2AADORA1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230151049-A1 | Compounds Useful in HIV Therapy | VIIV HEALTHCARE COMPANY (US) | 2023-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230151049-A1 | Compounds Useful in HIV Therapy | CCR5, CD4, NPC1 | SERPINA3 304/4885TMIGD3 4680/4885ADORA2A 2043/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.