SCHEMBL25527402

SCHEMBL25527402

O=C(O)CC12CC3CC(C1)CC(OCCOC(=O)CS)(C3)C2

nearest known ligand 0.47

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.47
ALDH1A1 P00352 4/20 0.43
THRB P10828 1/20 0.43
LMNA P02545 1/20 0.40
TSHR P16473 1/20 0.39
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
GAA P10253 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25527400 0.82 POLB (0.53) POLBALDH1A1THRBLMNATSHR
SCHEMBL25527396 0.82 PKM (0.40) ALDH1A1THRBTSHRMEN1KMT2A
SCHEMBL14433714 0.72 POLB (0.75) POLBALDH1A1THRBLMNATSHR
SCHEMBL13589979 0.72 POLB (0.75) POLBALDH1A1THRBLMNATSHR
SCHEMBL29838840 0.72 POLB (0.75) POLBALDH1A1THRBLMNATSHR
SCHEMBL14493662 0.72 POLB (0.75) POLBALDH1A1THRBLMNATSHR
SCHEMBL1058665 0.72 POLB (0.75) POLBALDH1A1THRBLMNATSHR
SCHEMBL14691655 0.68 POLB (0.39) POLBALDH1A1THRBLMNATSHR
SCHEMBL3289593 0.68 POLB (0.64) POLBALDH1A1THRBLMNATSHR
SCHEMBL12932439 0.68 POLB (0.51) POLBALDH1A1THRBLMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230152696-A1 POSITIVE RESIST COMPOSITION AND PATTERN FORMING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-05-18 US disclosed
US-20230152696-A1 POSITIVE RESIST COMPOSITION AND PATTERN FORMING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-05-18 US disclosed