SCHEMBL2552791

SCHEMBL2552791

C=C(C)C(=O)OCCC[Si](C)(OCC)OC(C)C

nearest known ligand 0.47

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.47
THRB P10828 1/20 0.45
POLB P06746 1/20 0.35
APEX1 P27695 1/20 0.35
HTT P42858 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
ALDH1A1 P00352 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1833574 0.92 TSHR (0.43) TSHRTHRBPOLBAPEX1HTT
SCHEMBL137902 0.91 TSHR (0.49) TSHRTHRBPOLBAPEX1HTT
SCHEMBL63717 0.90 TSHR (0.54) TSHRTHRBPOLBAPEX1HTT
SCHEMBL28347564 0.88 TSHR (0.53) TSHRTHRBPOLBAPEX1HTT
SCHEMBL31709677 0.88 TSHR (0.44) TSHRTHRBPOLBAPEX1HTT
Alcohol SCHEMBL28778173 0.87 TSHR (0.51) TSHRTHRBPOLBAPEX1HTT
SCHEMBL2545645 0.86 TSHR (0.47) TSHRTHRBPOLBAPEX1HTT
SCHEMBL2549570 0.85 TSHR (0.50) TSHRTHRBPOLBAPEX1HTT
SCHEMBL221515 0.85 TSHR (0.50) TSHRTHRBPOLBAPEX1HTT
Butanone SCHEMBL28158317 0.85 TSHR (0.50) TSHRTHRBPOLBAPEX1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2553145-B1 ETCH RESISTANT ALUMINA BASED COATINGS PIBOND OY (FI) 2022-09-21 EP disclosed
US-20170200615-A1 ETCH RESISTANT ALUMINA BASED COATINGS PIBOND (ZHEJIANG) NEW MATERIALS CO., LTD (CN) 2017-07-13 US disclosed
US-9564339-B2 Etch resistant alumina based coatings PIBOND OY (FI) 2017-02-07 US disclosed
US-20130143408-A1 ETCH RESISTANT ALUMINA BASED COATINGS SILECS OY (FI) 2013-06-06 US disclosed
EP-2553145-A1 ETCH RESISTANT ALUMINA BASED COATINGS Silecs OY (FI) 2013-02-06 EP disclosed
WO-2011121166-A1 ETCH RESISTANT ALUMINA BASED COATINGS SILECS OY (FI) 2011-10-06 WO disclosed