Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.40 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.40 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18690473 | 0.86 | HRH4 (0.50) | MEN1KMT2ATSHRALDH1A1HRH4 | |
| SCHEMBL25528429 | 0.84 | PIK3CA (0.49) | MEN1KMT2ASMN1; SMN2PIK3CATSHR | |
| SCHEMBL28061994 | 0.82 | KMT2A (0.47) | HTTMEN1RECQLKMT2AATM | |
| SCHEMBL28827424 | 0.80 | KMT2A (0.44) | HTTMEN1RECQLKMT2AATM | |
| SCHEMBL25528278 | 0.78 | PTPN11 (0.36) | KCNQ3KCNQ2TSHRALDH1A1PTPN11 | |
| SCHEMBL20089101 | 0.78 | PTPN11 (0.48) | HTTKMT2ASMN1; SMN2POLBPIK3CA | |
| SCHEMBL1776789 | 0.75 | PTPN11 (0.49) | HTTKMT2ASMN1; SMN2POLBPIK3CA | |
| SCHEMBL26647296 | 0.75 | PTPN11 (0.44) | HTTMEN1RECQLKMT2AATM | |
| SCHEMBL25528324 | 0.75 | BACE1 (0.33) | KCNQ3KCNQ2PTPN11 | |
| SCHEMBL27316944 | 0.75 | POLB (0.55) | SMN1; SMN2POLBKCNQ3KCNQ2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023078411-A1 | AZASPIRO COMPOUND | 南京明德新药研发有限公司 | 2023-05-11 | — | — | WO | disclosed |