Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 8/20 | 0.49 |
| ▸ | MTOR | P42345 | 6/20 | 0.49 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.49 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | PIK3R1 | P27986 | 5/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25528384 | 0.84 | HTT (0.46) | PIK3CAKMT2AALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL18690473 | 0.83 | HRH4 (0.50) | KMT2AALDH1A1MEN1CYP1A2TSHR | |
| SCHEMBL24158887 | 0.79 | PTPN11 (0.48) | PIK3CAMTORPIK3CDKMT2AKDM4E | |
| SCHEMBL5765855 | 0.79 | MAPK1 (0.50) | PIK3CAMTORKMT2AKDM4EPIK3R1 | |
| SCHEMBL26646893 | 0.79 | PIK3CA (0.55) | PIK3CAMTORPIK3CDPIK3CBKMT2A | |
| SCHEMBL10998627 | 0.76 | PIK3CA (0.52) | PIK3CAMTORPIK3CDPIK3CBKMT2A | |
| SCHEMBL24158953 | 0.76 | PTPN11 (0.51) | PIK3CDKDM4EALDH1A1SMN1; SMN2CYP1A2 | |
| SCHEMBL25528278 | 0.76 | PTPN11 (0.36) | ALDH1A1TSHRUSP2HSD17B10 | |
| SCHEMBL11697780 | 0.75 | KCNQ3 (0.47) | PIK3CAMTORKMT2AKDM4EPIK3R1 | |
| SCHEMBL2416637 | 0.74 | SMPD3 (0.47) | KMT2AKDM4EALDH1A1SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023078411-A1 | AZASPIRO COMPOUND | 南京明德新药研发有限公司 | 2023-05-11 | — | — | WO | disclosed |