Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 9/20 | 0.47 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.38 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.37 |
| ▸ | FYN | P06241 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | FLT4 | P35916 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.37 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.37 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25528965 | 0.81 | ADORA2A (0.52) | MAPK14DYRK1AADORA2AADORA1ADORA2B | |
| SCHEMBL25208823 | 0.78 | ADORA2A (0.47) | MAPK14DYRK1AADORA2AADORA1ADORA2B | |
| SCHEMBL25528882 | 0.78 | SMN1; SMN2 (0.39) | MAPK14ABL1EGFRMAPK1KDR | |
| SCHEMBL20600738 | 0.77 | GRIA1 (0.48) | MAPK14DYRK1AADORA2AADORA1ADORA2B | |
| SCHEMBL25528877 | 0.76 | ADORA2A (0.45) | MAPK14ADORA2AADORA1ADORA2BPDE4A | |
| SCHEMBL18041561 | 0.76 | MAPK14 (0.61) | MAPK14DYRK1AADORA2AADORA1ADORA2B | |
| SCHEMBL29676815 | 0.76 | MAPK14 (0.61) | MAPK14DYRK1AADORA2AADORA1ADORA2B | |
| SCHEMBL20600796 | 0.74 | ADORA2A (0.46) | MAPK14DYRK1AADORA2AADORA1ADORA2B | |
| SCHEMBL21730197 | 0.74 | ADORA2A (0.57) | MAPK14DYRK1AADORA2AADORA1ADORA2B | |
| SCHEMBL29907552 | 0.74 | ADORA2A (0.57) | MAPK14DYRK1AADORA2AADORA1ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023091604-A1 | ADENOSINE RECEPTOR ANTAGONISTS | CROSSIGNAL THERAPEUTICS, INC. (US) | 2023-05-25 | — | — | WO | disclosed |