Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 9/20 | 0.39 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.39 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25528944 | 0.89 | KDM4E (0.36) | SMN1; SMN2KDM4ENPC1HCRTR1USP2 | |
| SCHEMBL25528998 | 0.82 | ADORA2A (0.41) | SMN1; SMN2KDM4ENPC1HCRTR1USP2 | |
| SCHEMBL25206204 | 0.79 | MAPK14 (0.40) | SMN1; SMN2KDM4ENPC1HCRTR1USP2 | |
| SCHEMBL30359478 | 0.79 | MAPK14 (0.40) | SMN1; SMN2KDM4ENPC1HCRTR1USP2 | |
| SCHEMBL20600598 | 0.78 | GRIA1 (0.48) | CCNA2CDK2CSNK1ECDK5CDK5R1 | |
| SCHEMBL25528890 | 0.78 | MAPK14 (0.47) | MAPK1MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL20666043 | 0.76 | MAPK14 (0.43) | SMN1; SMN2KDM4ENPC1HCRTR1USP2 | |
| SCHEMBL20600523 | 0.75 | GRIA1 (0.39) | SMN1; SMN2KDM4ENPC1HCRTR1USP2 | |
| SCHEMBL25528249 | 0.74 | ADORA2A (0.52) | — | |
| SCHEMBL20624497 | 0.74 | GRIA1 (0.40) | SMN1; SMN2KDM4ENPC1HCRTR1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023091604-A1 | ADENOSINE RECEPTOR ANTAGONISTS | CROSSIGNAL THERAPEUTICS, INC. (US) | 2023-05-25 | — | — | WO | disclosed |