Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 13/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 12/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 11/20 | 0.38 |
| ▸ | USP2 | O75604 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25528986 | 0.88 | ADORA2A (0.38) | ADORA2AADORA1ADORA2BPIK3CAMAP4K4 | |
| SCHEMBL25528882 | 0.82 | SMN1; SMN2 (0.39) | USP2KDM4ENPC1HCRTR1ALDH1A1 | |
| SCHEMBL25528956 | 0.79 | ADORA2A (0.56) | ADORA2AADORA1ADORA2B | |
| SCHEMBL25216212 | 0.79 | ADORA2A (0.44) | ADORA2AADORA1ADORA2B | |
| SCHEMBL30359475 | 0.79 | ADORA2A (0.44) | ADORA2AADORA1ADORA2B | |
| SCHEMBL25528965 | 0.78 | ADORA2A (0.52) | ADORA2AADORA1ADORA2BMAPK14CYP3A4 | |
| SCHEMBL29165055 | 0.76 | NR4A2 (0.42) | USP2KDM4ENPC1HCRTR1ALDH1A1 | |
| SCHEMBL25528944 | 0.74 | KDM4E (0.36) | ADORA2AUSP2KDM4ENPC1HCRTR1 | |
| SCHEMBL30738436 | 0.72 | HRH2 (0.44) | ADORA2AADORA1ADORA2BUSP2KDM4E | |
| SCHEMBL22163950 | 0.72 | HRH2 (0.44) | ADORA2AADORA1ADORA2BUSP2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023091604-A1 | ADENOSINE RECEPTOR ANTAGONISTS | CROSSIGNAL THERAPEUTICS, INC. (US) | 2023-05-25 | — | — | WO | disclosed |