Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | CDK8 | P49336 | 1/20 | 0.47 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.47 |
| ▸ | HTR7 | P34969 | 2/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.44 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 3/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12944870 | 0.84 | MAPT (0.47) | MAPTCDK8ACVR1HTR7PRMT5 | |
| SCHEMBL10176300 | 0.81 | HTR7 (0.43) | MAPTCDK8ACVR1HTR7PRMT5 | |
| SCHEMBL12362814 | 0.81 | HTR7 (0.51) | MAPTCDK8ACVR1HTR7PRMT5 | |
| SCHEMBL20320421 | 0.80 | MAPT (0.67) | MAPTCDK8ACVR1HTR7HTR1A | |
| SCHEMBL25528557 | 0.79 | MAPT (0.40) | MAPTCDK8ACVR1KEAP1NPC1 | |
| SCHEMBL4021817 | 0.79 | MAPT (0.44) | MAPTCDK8ACVR1HTR7PRMT5 | |
| SCHEMBL29980120 | 0.79 | HTR7 (0.56) | MAPTCDK8ACVR1HTR7PRMT5 | |
| SCHEMBL27088353 | 0.79 | HTR7 (0.56) | MAPTCDK8ACVR1HTR7PRMT5 | |
| SCHEMBL30231192 | 0.79 | MAPT (0.44) | MAPTCDK8ACVR1HTR7PRMT5 | |
| SCHEMBL10145036 | 0.78 | HTR7 (0.43) | MAPTCDK8ACVR1HTR7PRMT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4183783-A1 | IMMUNOMODULATOR | Hitgen Inc. (CN) | 2023-05-24 | — | — | EP | disclosed |