Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.43 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.43 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.43 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | GALR3 | O60755 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL27674414 | 0.90 | TSHR (0.50) | TSHRL3MBTL1GAANOTUMKDM4E | |
| SCHEMBL2818597 | 0.83 | TSHR (0.63) | TSHRGAAKDM4EALDH1A1HTT | |
| SCHEMBL57480 | 0.83 | TSHR (0.63) | TSHRGAAKDM4EALDH1A1HTT | |
| Water SCHEMBL27896186 | 0.83 | TSHR (0.63) | TSHRGAAKDM4EALDH1A1HTT | |
| SCHEMBL29352197 | 0.83 | TSHR (0.63) | TSHRGAAKDM4EALDH1A1HTT | |
| Water SCHEMBL19410621 | 0.83 | TSHR (0.63) | TSHRGAAKDM4EALDH1A1HTT | |
| SCHEMBL180961 | 0.81 | ALDH1A1 (0.48) | TSHRL3MBTL1KDM4EALDH1A1HTT | |
| Formaldehyde SCHEMBL28231823 | 0.80 | TSHR (0.55) | TSHRL3MBTL1GAAKDM4EALDH1A1 | |
| Acetonitrile SCHEMBL9500953 | 0.80 | TSHR (0.62) | TSHRL3MBTL1GAAKDM4EALDH1A1 | |
| SCHEMBL6372765 | 0.80 | TSHR (0.60) | TSHRGAAKDM4EALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140148596-A1 | Covalent Organic Frameworks and Methods of Making Same | CORNELL UNIVERSITY (US) | 2014-05-29 | — | — | US | disclosed |
| WO-2011127301-A2 | COVALENT ORGANIC FRAMEWORKS AND METHODS OF MAKING SAME | CORNELL UNIVERSITY (US) | 2011-10-13 | — | — | WO | disclosed |