SCHEMBL25529702

SCHEMBL25529702

Nc1ccc(F)c(Br)c1OC(F)F

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SCN9A Q15858 1/20 0.32
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16755889 0.84
SCHEMBL6649047 0.80 SCN9A (0.33) SCN9AALDH1A1
SCHEMBL25529592 0.76 ALOX5AP (0.38) ALDH1A1
SCHEMBL30079408 0.76 ALOX5AP (0.38) ALDH1A1
SCHEMBL30695904 0.76 SCN9A (0.36) SCN9AALDH1A1
SCHEMBL19951611 0.73 ALOX5AP (0.36) ALDH1A1
SCHEMBL6375248 0.72 SCN9A (0.45) SCN9AALDH1A1
SCHEMBL5699178 0.71 SCN9A (0.33) SCN9AALDH1A1
SCHEMBL30079497 0.71 SCN9A (0.33) SCN9AALDH1A1
SCHEMBL9125982 0.69 TSHR (0.31) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023078411-A1 AZASPIRO COMPOUND 南京明德新药研发有限公司 2023-05-11 WO disclosed