Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 5/20 | 0.43 |
| ▸ | MAP4K1 | Q92918 | 3/20 | 0.43 |
| ▸ | ALK | Q9UM73 | 12/20 | 0.42 |
| ▸ | INSR | P06213 | 4/20 | 0.42 |
| ▸ | IGF1R | P08069 | 4/20 | 0.42 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.41 |
| ▸ | ROS1 | P08922 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25530272 | 0.85 | MAP4K1 (0.61) | EGFRMAP4K1ALKINSRIGF1R | |
| SCHEMBL25529423 | 0.85 | ALK (0.45) | EGFRMAP4K1ALKINSRIGF1R | |
| SCHEMBL25527886 | 0.82 | ALK (0.42) | EGFRALKINSRIGF1RMAP3K7 | |
| SCHEMBL25527663 | 0.80 | ALK (0.44) | EGFRALKINSRIGF1RMAP3K7 | |
| SCHEMBL25529757 | 0.78 | ALK (0.42) | EGFRALKINSRIGF1RMAP3K7 | |
| SCHEMBL18831987 | 0.78 | ALK (0.56) | EGFRMAP4K1ALKINSRIGF1R | |
| SCHEMBL25530712 | 0.78 | ALK (0.42) | EGFRALKINSRIGF1RMAP3K7 | |
| SCHEMBL25529446 | 0.78 | ALK (0.51) | EGFRMAP4K1ALKINSRIGF1R | |
| SCHEMBL25527989 | 0.76 | ALK (0.45) | EGFRALKINSRIGF1RROS1 | |
| SCHEMBL25530918 | 0.76 | ALK (0.42) | EGFRMAP4K1ALKINSRIGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023078411-A1 | AZASPIRO COMPOUND | 南京明德新药研发有限公司 | 2023-05-11 | — | — | WO | disclosed |