SCHEMBL25530263

SCHEMBL25530263

Oc1ccc(Nc2ncnc3ccccc23)cc1I

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABCG2 Q9UNQ0 8/20 0.65
EGFR P00533 8/20 0.64
HTT P42858 2/20 0.64
GLA P06280 1/20 0.64
GAA P10253 1/20 0.63
DAPK3 O43293 1/20 0.59
MAP4K4 O95819 1/20 0.59
ABL1 P00519 1/20 0.59
ERBB2 P04626 1/20 0.59
PIM1 P11309 1/20 0.59
PRKACA P17612 1/20 0.59
LTK P29376 1/20 0.59
MAPK8 P45983 1/20 0.59
CSNK1A1 P48729 1/20 0.59
RPS6KA3 P51812 1/20 0.59
LIMK1 P53667 1/20 0.59
MAP2K1 Q02750 1/20 0.59
ACVR1 Q04771 1/20 0.59
TYRO3 Q06418 1/20 0.59
MAP4K2 Q12851 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13138547 0.81 EGFR (0.67) ABCG2EGFRHTTGLAGAA
SCHEMBL9017040 0.80 ABCG2 (0.60) ABCG2EGFRHTTGLAGAA
SCHEMBL29894633 0.79 ABCG2 (1.00) ABCG2EGFRHTTGLAGAA
SCHEMBL4478882 0.79 ABCG2 (1.00) ABCG2EGFRHTTGLAGAA
SCHEMBL5570698 0.79 EGFR (0.75) ABCG2EGFRHTTGLAGAA
SCHEMBL4356660 0.78 EGFR (1.00) ABCG2EGFRHTTGLADAPK3
SCHEMBL5569900 0.78 HTT (1.00) ABCG2EGFRHTTGLAGAA
Hydrochloric Acid SCHEMBL7540312 0.78 RET (0.47) ABCG2EGFRHTTLCK
SCHEMBL7112009 0.78 KDR (0.76) ABCG2EGFRLCK
SCHEMBL13138549 0.77 ABCG2 (0.64) ABCG2EGFRHTTGLAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023085392-A1 ANTI-SARS-COV-2 DRUG 国立大学法人鹿児島大学 2023-05-19 WO disclosed