Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.78 |
| ▸ | GAA | P10253 | 1/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.46 |
| ▸ | KCNA5 | P22460 | 3/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.45 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL628330 | 0.90 | LMNA (0.96) | LMNAGAAALDH1A1MEN1KMT2A | |
| SCHEMBL2227113 | 0.90 | LMNA (0.96) | LMNAGAAALDH1A1MEN1KMT2A | |
| SCHEMBL15063248 | 0.88 | GAA (0.96) | LMNAGAAALDH1A1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL15063253 | 0.88 | LMNA (1.00) | LMNAGAAALDH1A1MEN1KMT2A | |
| SCHEMBL2554530 | 0.88 | GAA (0.96) | LMNAGAAALDH1A1MEN1KMT2A | |
| SCHEMBL1808956 | 0.88 | GAA (0.96) | LMNAGAAALDH1A1MEN1KMT2A | |
| SCHEMBL628011 | 0.88 | GAA (0.96) | LMNAGAAALDH1A1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL2988022 | 0.86 | GAA (1.00) | LMNAGAAALDH1A1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL629184 | 0.86 | GAA (1.00) | LMNAGAAALDH1A1MEN1KMT2A | |
| SCHEMBL18061849 | 0.86 | LMNA (0.89) | LMNAGAAALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011123937-A1 | KINASE INHIBITORS AND METHOD OF TREATING CANCER WITH SAME | UNIVERSITY HEALTH NETWORK (CA) | 2011-10-13 | — | — | WO | disclosed |