Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | NQO2 | P16083 | 1/20 | 0.45 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.41 |
| ▸ | PGR | P06401 | 2/20 | 0.41 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.41 |
| ▸ | AR | P10275 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | TUBB4A | P04350 | 5/20 | 0.39 |
| ▸ | TUBB | P07437 | 5/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 5/20 | 0.39 |
| ▸ | TUBA1B | P68363 | 5/20 | 0.39 |
| ▸ | TUBA4A | P68366 | 5/20 | 0.39 |
| ▸ | TUBB4B | P68371 | 5/20 | 0.39 |
| ▸ | TUBB3 | Q13509 | 5/20 | 0.39 |
| ▸ | TUBB2A | Q13885 | 5/20 | 0.39 |
| ▸ | TUBB8 | Q3ZCM7 | 5/20 | 0.39 |
| ▸ | TUBA3E | Q6PEY2 | 5/20 | 0.39 |
| ▸ | TUBA1A | Q71U36 | 5/20 | 0.39 |
| ▸ | TUBA1C | Q9BQE3 | 5/20 | 0.39 |
| ▸ | TUBB6 | Q9BUF5 | 5/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15331110 | 0.90 | ALDH1A1 (0.50) | ALDH1A1NQO2NR3C1PGRNR3C2 | |
| SCHEMBL15330435 | 0.88 | ALDH1A1 (0.52) | ALDH1A1NQO2NR3C1PGRNR3C2 | |
| SCHEMBL15330343 | 0.86 | MAPK13 (0.42) | ALDH1A1ARHTTMEN1KMT2A | |
| SCHEMBL15332951 | 0.85 | PARP1 (0.39) | ALDH1A1ARHTTMEN1POLB | |
| SCHEMBL2553852 | 0.84 | ALDH1A1 (0.51) | ALDH1A1NQO2NR3C1PGRNR3C2 | |
| SCHEMBL2560581 | 0.84 | ALDH1A1 (0.51) | ALDH1A1NQO2NR3C1PGRNR3C2 | |
| SCHEMBL15330423 | 0.84 | ALDH1A1 (0.53) | ALDH1A1NQO2NR3C1PGRNR3C2 | |
| SCHEMBL2559370 | 0.82 | MAPK14 (0.37) | ALDH1A1HTTMEN1POLBKMT2A | |
| SCHEMBL15332034 | 0.82 | ALDH1A1 (0.54) | ALDH1A1NQO2NR3C1PGRNR3C2 | |
| SCHEMBL15331732 | 0.82 | ALDH1A1 (0.54) | ALDH1A1NQO2NR3C1PGRNR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| US-11225655-B2 | Bi-functional complexes and methods for making and using such complexes | NUEVOLUTION A/S (DK) | 2022-01-18 | — | — | US | disclosed |
| EP-3540059-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2019-09-18 | — | — | EP | disclosed |
| EP-2558577-B1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION AS (DK) | 2018-12-12 | — | — | EP | disclosed |
| US-20130281324-A1 | BI-FUNCTINAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2013-10-24 | — | — | US | disclosed |
| EP-2558577-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2013-02-20 | — | — | EP | disclosed |
| WO-2011127933-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2011-10-20 | — | — | WO | disclosed |