SCHEMBL25530864

SCHEMBL25530864

CCCCCCCCC(CCCCCCCC)OC(=O)CCCCCCCN(CCCCCCCC(=O)OC(CCCCCCCC)CCCCCCCC)CCN1CCN(CCN(CCCCCCCC(=O)OC(CCCCCCCC)CCCCCCCC)CCCCCCCC(=O)OC(CCCCCCCC)CCCCCCCC)CC1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 3/20 0.48
MAPT P10636 2/20 0.48
LMNA P02545 4/20 0.46
ALDH1A1 P00352 1/20 0.46
PRKCA P17252 1/20 0.43
PRKCE Q02156 1/20 0.43
PRKCQ Q04759 1/20 0.43
PRKCD Q05655 1/20 0.43
GAA P10253 1/20 0.42
CYP1A2 P05177 2/20 0.40
TP53 P04637 2/20 0.40
TSHR P16473 2/20 0.40
MEN1 O00255 1/20 0.40
GMNN O75496 1/20 0.40
HSP90AA1 P07900 1/20 0.40
BLM P54132 1/20 0.40
KMT2A Q03164 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
NR1H4 Q96RI1 1/20 0.40
CYP2C9 P11712 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31663671 0.98 MAPK1 (0.46) MAPK1MAPTLMNAALDH1A1PRKCA
SCHEMBL25416159 0.96 MAPK1 (0.45) MAPK1MAPTLMNAALDH1A1PRKCA
SCHEMBL17367570 0.95 GAA (0.47) MAPK1MAPTLMNAALDH1A1PRKCA
SCHEMBL25418208 0.93 ALDH1A1 (0.46) MAPK1MAPTLMNAALDH1A1PRKCA
SCHEMBL25417070 0.93 ALDH1A1 (0.46) MAPK1MAPTLMNAALDH1A1PRKCA
SCHEMBL25529674 0.93 ALDH1A1 (0.46) MAPK1MAPTLMNAALDH1A1PRKCA
SCHEMBL25419620 0.93 ALDH1A1 (0.46) MAPK1MAPTLMNAALDH1A1PRKCA
SCHEMBL25529677 0.93 ALDH1A1 (0.46) MAPK1MAPTLMNAALDH1A1PRKCA
SCHEMBL25623384 0.93 TLR2 (0.48) MAPK1MAPTLMNAALDH1A1PRKCA
SCHEMBL27427505 0.93 MAPK1 (0.44) MAPK1MAPTLMNAALDH1A1PRKCA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024102434-A1 RNA COMPOSITIONS COMPRISING LIPID NANOPARTICLES OR LIPID RECONSTRUCTED NATURAL MESSENGER PACKS SENDA BIOSCIENCES, INC. (US) 2024-05-16 WO disclosed
WO-2023091787-A1 NOVEL IONIZABLE LIPIDS AND LIPID NANOPARTICLES AND METHODS OF USING THE SAME SENDA BIOSCIENCES, INC. (US) 2023-05-25 WO disclosed