SCHEMBL2553115

SCHEMBL2553115

CC(N1CCC(OC2CCC(Oc3cnc(S(C)(=O)=O)cn3)CC2)CC1)C(F)(F)F

nearest known ligand 0.69

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 20/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2553254 1.00 GPR119 (0.69) GPR119
SCHEMBL2553141 0.83 GPR119 (0.50) GPR119
SCHEMBL2553520 0.82 GPR119 (1.00) GPR119
SCHEMBL12283420 0.82 GPR119 (1.00) GPR119
SCHEMBL14634198 0.82 GPR119 (1.00) GPR119
SCHEMBL14634702 0.82 GPR119 (1.00) GPR119
SCHEMBL2553521 0.82 GPR119 (1.00) GPR119
SCHEMBL12283112 0.82 GPR119 (1.00) GPR119
SCHEMBL14634266 0.82 GPR119 (0.70) GPR119
SCHEMBL14634264 0.82 GPR119 (0.70) GPR119

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011127051-A1 MODULATORS OF THE GPR119 RECEPTOR AND THE TREATMENT OF DISORDERS RELATED THERETO ARENA PHARMACEUTICALS, INC. (US) 2011-10-13 WO disclosed