Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 8/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 8/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.52 |
| ▸ | HTR2C | P28335 | 8/20 | 0.51 |
| ▸ | HTR1A | P08908 | 5/20 | 0.45 |
| ▸ | HTR6 | P50406 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17080017 | 0.90 | KDM4E (0.46) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6910863 | 0.86 | SLC6A2 (0.50) | SLC6A2SLC6A4SLC6A3HTR2CHTR1A | |
| SCHEMBL14635403 | 0.86 | SLC6A2 (0.50) | SLC6A2SLC6A4SLC6A3HTR2CHTR1A | |
| Hydrochloric Acid SCHEMBL1660306 | 0.85 | HTR2C (0.50) | SLC6A2SLC6A4SLC6A3HTR2CHTR1A | |
| SCHEMBL12284513 | 0.84 | HTR2A (0.47) | SLC6A2SLC6A4SLC6A3HTR2C | |
| SCHEMBL27747024 | 0.84 | HTR2A (0.47) | SLC6A2SLC6A4SLC6A3HTR2C | |
| SCHEMBL21767469 | 0.83 | KDM4E (0.41) | — | |
| SCHEMBL31072042 | 0.83 | KDM4E (0.41) | — | |
| SCHEMBL12281735 | 0.82 | SLC6A2 (0.57) | SLC6A2SLC6A4SLC6A3HTR2CHTR1A | |
| SCHEMBL10864121 | 0.78 | SLC6A2 (0.59) | SLC6A2SLC6A4SLC6A3HTR2CHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011123937-A1 | KINASE INHIBITORS AND METHOD OF TREATING CANCER WITH SAME | UNIVERSITY HEALTH NETWORK (CA) | 2011-10-13 | — | — | WO | disclosed |
| WO-2011123937-A1 | KINASE INHIBITORS AND METHOD OF TREATING CANCER WITH SAME | UNIVERSITY HEALTH NETWORK (CA) | 2011-10-13 | — | — | WO | disclosed |