Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 7/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.50 |
| ▸ | HTR2C | P28335 | 6/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21767564 | 0.90 | PKM (0.48) | SLC6A2SLC6A4SLC6A3PKM | |
| SCHEMBL2553239 | 0.86 | SLC6A2 (0.52) | SLC6A2SLC6A4SLC6A3HTR2CHTR1A | |
| Hydrochloric Acid SCHEMBL1661070 | 0.86 | CYP4F2 (0.53) | SLC6A2SLC6A4SLC6A3HTR2CPKM | |
| SCHEMBL12281735 | 0.80 | SLC6A2 (0.57) | SLC6A2SLC6A4SLC6A3HTR2CHTR1A | |
| SCHEMBL10864121 | 0.79 | SLC6A2 (0.59) | SLC6A2SLC6A4SLC6A3HTR2CHTR1A | |
| SCHEMBL3676421 | 0.78 | TSHR (0.56) | HTR2C | |
| SCHEMBL14635943 | 0.76 | L3MBTL1 (0.51) | PKMMAPT | |
| SCHEMBL6910863 | 0.76 | SLC6A2 (0.50) | SLC6A2SLC6A4SLC6A3HTR2CHTR1A | |
| SCHEMBL68340 | 0.75 | PKM (0.60) | PKM | |
| SCHEMBL17080017 | 0.75 | KDM4E (0.46) | SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013010453-A1 | CHEMOKING RECEPTOR ANTAGONISTS | ABBOTT LABORATORIES (US) | 2013-01-24 | — | — | WO | disclosed |