Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 15/20 | 0.51 |
| ▸ | CTSS | P25774 | 4/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28668065 | 0.87 | CTSK (0.50) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL28668062 | 0.87 | CTSK (0.50) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL25985137 | 0.87 | CTSK (0.50) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL14533725 | 0.86 | CTSK (0.49) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL15959879 | 0.85 | CA1 (0.50) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL26035614 | 0.85 | CA1 (0.50) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL24427425 | 0.85 | CA1 (0.53) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL13605079 | 0.85 | CA1 (0.53) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL2681437 | 0.84 | CTSK (0.43) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL2681435 | 0.84 | CTSK (0.43) | CTSKCTSSCA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4180431-A1 | CHEMICAL COMPOUNDS | GlaxoSmithKline Intellectual Property Development Limited (GB) | 2023-05-17 | — | — | EP | disclosed |