Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | POLQ | O75417 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.41 |
| ▸ | PPARG | P37231 | 4/20 | 0.41 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ACP3 | P15309 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8915633 | 0.82 | CNR2 (0.43) | KDM4EALDH1A1POLQCNR2KMT2A | |
| SCHEMBL29268488 | 0.81 | EPHX2 (0.46) | KDM4EALDH1A1EPHX2PPARGCNR2 | |
| SCHEMBL2550492 | 0.80 | TDP1 (0.43) | KDM4EALDH1A1KMT2ASLC6A2SLC6A4 | |
| SCHEMBL753073 | 0.80 | POLQ (0.47) | POLQPPARGCNR2ACP3 | |
| SCHEMBL8921824 | 0.80 | ACP3 (0.43) | ALDH1A1POLQCNR2ACP3POLB | |
| SCHEMBL6929206 | 0.79 | KDM4E (0.44) | KDM4EALDH1A1EPHX2PPARGCNR2 | |
| SCHEMBL2550711 | 0.79 | PIN1 (0.41) | KDM4EALDH1A1KMT2ASLC6A2SLC6A4 | |
| SCHEMBL888787 | 0.78 | POLQ (0.41) | ALDH1A1POLQCNR2SLC6A2SLC6A4 | |
| SCHEMBL8907146 | 0.78 | ACP3 (0.41) | ALDH1A1POLQCNR2ACP3POLB | |
| SCHEMBL167566 | 0.77 | EPHX2 (0.44) | KDM4EALDH1A1EPHX2PPARGCNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011123937-A1 | KINASE INHIBITORS AND METHOD OF TREATING CANCER WITH SAME | UNIVERSITY HEALTH NETWORK (CA) | 2011-10-13 | — | — | WO | disclosed |