SCHEMBL2553642

SCHEMBL2553642

CCCO[Si](OCCC)(OCCC)c1cccc2cc3ccccc3cc12

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPBAR1 Q8TDU6 3/20 0.37
CYSLTR1 Q9Y271 2/20 0.37
TLR8 Q9NR97 2/20 0.35
NQO1 P15559 1/20 0.34
KDM4E B2RXH2 1/20 0.33
ALDH1A1 P00352 1/20 0.33
GAA P10253 1/20 0.33
CYSLTR2 Q9NS75 1/20 0.33
BTK Q06187 1/20 0.33
MEN1 O00255 1/20 0.33
MAPT P10636 1/20 0.33
KMT2A Q03164 1/20 0.33
ABCB11 O95342 1/20 0.32
LMNA P02545 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP2D6 P10635 1/20 0.32
SCN1A P35498 1/20 0.32
SCN2A Q99250 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
SCN3A Q9NY46 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29777530 0.87 NQO1 (0.36) TLR8NQO1KDM4EALDH1A1GAA
SCHEMBL935775 0.87 NQO1 (0.36) TLR8NQO1KDM4EALDH1A1GAA
SCHEMBL4585248 0.85 NQO1 (0.35) TLR8NQO1KDM4EALDH1A1GAA
SCHEMBL27686189 0.85 NQO1 (0.35) TLR8NQO1KDM4EALDH1A1GAA
SCHEMBL4584706 0.85 NQO1 (0.35) TLR8NQO1KDM4EALDH1A1GAA
SCHEMBL106133 0.85 HTR1B (0.41) ALDH1A1GAAMEN1KMT2ACYP1A2
SCHEMBL30528215 0.85 HTR1B (0.41) ALDH1A1GAAMEN1KMT2ACYP1A2
SCHEMBL2352242 0.84 NPC1 (0.33) NQO1MAPT
SCHEMBL3293356 0.83 GPBAR1 (0.35) GPBAR1CYSLTR1TLR8NQO1KDM4E
SCHEMBL17600572 0.83 ALDH1A1 (0.40) GPBAR1CYSLTR1NQO1KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2553145-B1 ETCH RESISTANT ALUMINA BASED COATINGS PIBOND OY (FI) 2022-09-21 EP disclosed
US-20170200615-A1 ETCH RESISTANT ALUMINA BASED COATINGS PIBOND (ZHEJIANG) NEW MATERIALS CO., LTD (CN) 2017-07-13 US disclosed
US-9564339-B2 Etch resistant alumina based coatings PIBOND OY (FI) 2017-02-07 US disclosed
US-20130143408-A1 ETCH RESISTANT ALUMINA BASED COATINGS SILECS OY (FI) 2013-06-06 US disclosed
EP-2553145-A1 ETCH RESISTANT ALUMINA BASED COATINGS Silecs OY (FI) 2013-02-06 EP disclosed
WO-2011121166-A1 ETCH RESISTANT ALUMINA BASED COATINGS SILECS OY (FI) 2011-10-06 WO disclosed