Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHGDH | O43175 | 20/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20768585 | 0.90 | PHGDH (0.58) | PHGDH | |
| SCHEMBL20768586 | 0.90 | PHGDH (0.58) | PHGDH | |
| SCHEMBL23393446 | 0.89 | PHGDH (0.45) | PHGDH | |
| SCHEMBL19347499 | 0.81 | PHGDH (0.58) | PHGDH | |
| SCHEMBL19343129 | 0.81 | PHGDH (0.54) | PHGDH | |
| SCHEMBL20794390 | 0.81 | PHGDH (0.63) | PHGDH | |
| SCHEMBL20768590 | 0.80 | PHGDH (0.56) | PHGDH | |
| SCHEMBL19347381 | 0.80 | PHGDH (0.56) | PHGDH | |
| SCHEMBL23393439 | 0.80 | PHGDH (0.45) | PHGDH | |
| SCHEMBL26326966 | 0.79 | PHGDH (0.45) | PHGDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3426244-B1 | 3-PHOSPHOGLYCERATE DEHYDROGENASE INHIBITORS AND USES THEREOF | RAZE THERAPEUTICS INC (US) | 2023-06-07 | — | — | EP | disclosed |