SCHEMBL2553693

SCHEMBL2553693

C/C=C/C=C/C(=O)OOC(=O)/C=C/C=C/C

nearest known ligand 0.38

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 2/20 0.38
LMNA P02545 1/20 0.38
HTT P42858 1/20 0.38
KEAP1 Q14145 1/20 0.35
NFE2L2 Q16236 1/20 0.35
HCAR2 Q8TDS4 1/20 0.35
ALDH1A1 P00352 1/20 0.35
CNR2 P34972 6/20 0.33
CNR1 P21554 4/20 0.33
PPARG P37231 1/20 0.33
PPARD Q03181 1/20 0.33
PPARA Q07869 1/20 0.33
EDNRA P25101 3/20 0.32
TRPA1 O75762 1/20 0.32
RAB9A P51151 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10478428 0.97 MAPK1 (0.37) MAPK1LMNAHTTKEAP1NFE2L2
SCHEMBL8067892 0.97 MAPK1 (0.37) MAPK1LMNAHTTKEAP1NFE2L2
SCHEMBL28287475 0.97 MAPK1 (0.37) MAPK1LMNAHTTKEAP1NFE2L2
SCHEMBL2128825 0.97 MAPK1 (0.37) MAPK1LMNAHTTKEAP1NFE2L2
SCHEMBL929157 0.97 MAPK1 (0.37) MAPK1LMNAHTTKEAP1NFE2L2
SCHEMBL1578006 0.95 LMNA (0.36) MAPK1LMNAHTTKEAP1NFE2L2
SCHEMBL16165978 0.84 LMNA (0.36) MAPK1LMNAHTTKEAP1NFE2L2
SCHEMBL111657 0.83 MAPK1 (0.38) MAPK1LMNAHTTKEAP1NFE2L2
SCHEMBL1907658 0.83 MAPK1 (0.38) MAPK1LMNAHTTKEAP1NFE2L2
SCHEMBL1907659 0.83 MAPK1 (0.38) MAPK1LMNAHTTKEAP1NFE2L2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023221936-A1 BIFUNCTIONAL PROTEIN, AND PREPARATION THEREOF AND USE THEREOF 苏州创胜医药集团有限公司 2023-11-23 WO disclosed
WO-2023204303-A1 CRYSTAL OF 7H-PYRROLO[2,3-D]PYRIMIDINE-4-AMINE DERIVATIVE 大鵬薬品工業株式会社 2023-10-26 WO disclosed
EP-4185124-A1 SPENT GRAIN-DERIVED FOOD ADDITIVE Biograin ApS (DK) 2023-05-31 EP disclosed
CN-114787200-A Method for forming inclusion complex using hydrophilic beta-cyclodextrin derivatives and compositions thereof 塔卡美国公司 2022-07-22 CN disclosed
US-10308732-B2 Package for pellets of saponified ethylene-vinyl ester-based copolymer or resin composition thereof THE NIPPON SYNTHETIC CHEMICAL INDUSTRY CO., LTD. (JP) 2019-06-04 US disclosed
CN-109090178-A Antimicrobial powder for baked product preparation 卡拉万成分股份有限公司 2018-12-28 CN disclosed
CN-108969469-A The preparation of 4 β of anti alpha, 7 antibody 米伦纽姆医药公司 2018-12-11 CN disclosed
CN-108969761-A The preparation of 4 β of anti alpha, 7 antibody 米伦纽姆医药公司 2018-12-11 CN disclosed
CN-107027307-A A kind of anti-infective compounds 韩国巴斯德研究所 2017-08-08 CN disclosed
CN-106879256-A 2 aminobenzimidazole derivatives and its application as 5 LOXs and/or prostaglandin-e synthetase inhibitors 韩国巴斯德研究所 2017-06-20 CN disclosed
EP-0999750-A1 ANTIFUNGAL COMPOSITION ZENECA LIMITED (GB) 2000-05-17 EP disclosed
EP-0933990-A1 INSECTICIDAL COMPOSITION R & C PRODUCTS PTY. LIMITED (AU) 1999-08-11 EP disclosed
WO-1999002038-A1 ANTIFUNGAL COMPOSITION ZENECA LIMITED (GB) 1999-01-21 WO disclosed
WO-1998009515-A1 INSECTICIDAL COMPOSITION R & C PRODUCTS PTY. LIMITED (AU) 1998-03-12 WO disclosed
CN-1175899-A Method for inhibiting sorbate-induced brown discoloration in food and cosmetic compositions HOECHST AG (DE) 1998-03-11 CN disclosed
EP-0804156-A1 ENZYME CONTAINING EFFERVESCENT CLEANING TABLET SOUTHLAND, LTD. (US) 1997-11-05 EP disclosed
EP-0762868-A1 MILD ANTIMICROBIAL LIQUID CLEANSING FORMULATIONS UNILEVER PLC (GB) 1997-03-19 EP disclosed
US-5529788-A CONTAINING PROTEOLYTIC ENZYME; FOR CLEANING DENTAL AND MEDICAL EQUIPMENT SOUTHLAND, LTD. (US) 1996-06-25 US disclosed
WO-1996010988-A1 ENZYME CONTAINING EFFERVESCENT CLEANING TABLET SOUTHLAND, LTD. (US) 1996-04-18 WO disclosed
WO-1995032705-A1 MILD ANTIMICROBIAL LIQUID CLEANSING FORMULATIONS UNILEVER PLC (GB) 1995-12-07 WO disclosed