Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 20/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL255384 | 0.85 | PTGER1 (0.56) | PTGER1 | |
| SCHEMBL3433815 | 0.85 | PTGER1 (0.64) | PTGER1CYP2C9CYP1A2CYP2C19 | |
| SCHEMBL18560414 | 0.85 | PTGER1 (0.67) | PTGER1CYP2C9CYP1A2CYP2C19 | |
| SCHEMBL3434489 | 0.84 | PTGER1 (0.61) | PTGER1 | |
| SCHEMBL3433669 | 0.84 | PTGER1 (0.62) | PTGER1CYP2C9CYP1A2CYP2C19 | |
| SCHEMBL3435608 | 0.84 | PTGER1 (0.61) | PTGER1CYP2C9CYP1A2CYP2C19 | |
| SCHEMBL19547231 | 0.82 | PTGER1 (0.62) | PTGER1CYP2C9CYP1A2CYP2C19 | |
| SCHEMBL3435950 | 0.80 | PTGER1 (0.60) | PTGER1CYP2C9CYP1A2CYP2C19 | |
| SCHEMBL14956245 | 0.79 | PTGER1 (0.59) | PTGER1CYP2C9CYP1A2CYP2C19 | |
| SCHEMBL4683984 | 0.79 | PTGER1 (0.85) | PTGER1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2588459-A1 | COMPOUNDS ACT AT MULTIPLE PROSTAGLANDIN RECEPTORS GIVING A GENERAL ANTI-INFLAMMATORY RESPONSE | Allergan, Inc. (US) | 2013-05-08 | — | — | EP | disclosed |
| WO-2012003414-A1 | COMPOUNDS ACT AT MULTIPLE PROSTAGLANDIN RECEPTORS GIVING A GENERAL ANTI-INFLAMMATORY RESPONSE | ALLERGAN, INC. (US) | 2012-01-05 | — | — | WO | disclosed |