SCHEMBL255384

SCHEMBL255384

Cc1cc(CCC=O)nn1Cc1cc(Cl)ccc1OCc1ccc(Cl)cc1

nearest known ligand 0.56

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PTGER1 P34995 20/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18560414 0.85 PTGER1 (0.67) PTGER1
SCHEMBL255383 0.85 PTGER1 (0.56) PTGER1
SCHEMBL3433815 0.85 PTGER1 (0.64) PTGER1
SCHEMBL3434489 0.84 PTGER1 (0.61) PTGER1
SCHEMBL3435950 0.84 PTGER1 (0.60) PTGER1
SCHEMBL3433669 0.84 PTGER1 (0.62) PTGER1
SCHEMBL3435608 0.84 PTGER1 (0.61) PTGER1
SCHEMBL19547231 0.82 PTGER1 (0.62) PTGER1
SCHEMBL14956245 0.79 PTGER1 (0.59) PTGER1
SCHEMBL4683984 0.79 PTGER1 (0.85) PTGER1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2588459-A1 COMPOUNDS ACT AT MULTIPLE PROSTAGLANDIN RECEPTORS GIVING A GENERAL ANTI-INFLAMMATORY RESPONSE Allergan, Inc. (US) 2013-05-08 EP disclosed
WO-2012003414-A1 COMPOUNDS ACT AT MULTIPLE PROSTAGLANDIN RECEPTORS GIVING A GENERAL ANTI-INFLAMMATORY RESPONSE ALLERGAN, INC. (US) 2012-01-05 WO disclosed