Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 19/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14634289 | 0.85 | GPR119 (0.69) | GPR119CYP2C9CYP2C19 | |
| SCHEMBL14634288 | 0.85 | GPR119 (0.69) | GPR119CYP2C9CYP2C19 | |
| SCHEMBL2556509 | 0.82 | GPR119 (0.73) | GPR119CYP2C9CYP2C19 | |
| SCHEMBL2556510 | 0.82 | GPR119 (0.73) | GPR119CYP2C9CYP2C19 | |
| SCHEMBL14634463 | 0.81 | GPR119 (0.64) | GPR119 | |
| SCHEMBL14634466 | 0.81 | GPR119 (0.64) | GPR119 | |
| SCHEMBL14634344 | 0.80 | GPR119 (0.71) | GPR119CYP2C9CYP2C19 | |
| SCHEMBL14634342 | 0.80 | GPR119 (0.74) | GPR119CYP2C9CYP2C19 | |
| SCHEMBL13734434 | 0.80 | GPR119 (0.76) | GPR119CYP2C9CYP2C19 | |
| SCHEMBL2556461 | 0.79 | GPR119 (0.61) | GPR119CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2556056-A1 | MODULATORS OF THE GPR119 RECEPTOR AND THE TREATMENT OF DISORDERS RELATED THERETO | Arena Pharmaceuticals, Inc. (US) | 2013-02-13 | — | — | EP | disclosed |
| WO-2011127051-A1 | MODULATORS OF THE GPR119 RECEPTOR AND THE TREATMENT OF DISORDERS RELATED THERETO | ARENA PHARMACEUTICALS, INC. (US) | 2011-10-13 | — | — | WO | disclosed |