Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 2/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25477218 | 0.84 | USP2 (0.40) | ADORA1NR1H2USP2SMN1; SMN2ESR2 | |
| SCHEMBL13048672 | 0.78 | ESR2 (0.46) | ADORA1NR1H2USP2SMN1; SMN2ESR2 | |
| SCHEMBL12435353 | 0.78 | NR1H2 (0.44) | ADORA1NR1H2USP2SMN1; SMN2ESR2 | |
| SCHEMBL24188025 | 0.77 | NR1H2 (0.51) | ADORA1NR1H2USP2SMN1; SMN2ESR2 | |
| SCHEMBL2493397 | 0.73 | NR1H2 (0.41) | ADORA1NR1H2USP2SMN1; SMN2ESR2 | |
| SCHEMBL2292608 | 0.73 | USP2 (0.52) | NR1H2USP2SMN1; SMN2ESR2NAMPT | |
| SCHEMBL16786413 | 0.72 | USP2 (0.41) | NR1H2USP2SMN1; SMN2ESR2NAMPT | |
| SCHEMBL22056057 | 0.72 | NR1H2 (0.40) | ADORA1NR1H2USP2SMN1; SMN2ESR2 | |
| SCHEMBL120243 | 0.71 | USP2 (0.50) | NR1H2USP2SMN1; SMN2ESR2HDAC1 | |
| SCHEMBL13801225 | 0.71 | USP2 (0.50) | NR1H2USP2SMN1; SMN2ESR2HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4186907-A1 | JAK INHIBITOR COMPOUND FOR TREATING SEVERE PNEUMONIA | Henan Medinno Pharmaceutical Technology Co., Ltd. (CN) | 2023-05-31 | — | — | EP | disclosed |