Acetamide

Acetamide

SCHEMBL2554280

C=CN(C)C(C)=O.CC(N)=O

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.42
ALOX15 P16050 1/20 0.42
BLM P54132 1/20 0.42
PMP22 Q01453 1/20 0.42
ALDH1A1 P00352 2/20 0.36
TSHR P16473 1/20 0.36
FGFR4 P22455 1/20 0.36
TDP1 Q9NUW8 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL35307 0.92
Acrylamide SCHEMBL7456424 0.90 ALDH1A1 (0.52) LMNAALOX15BLMPMP22ALDH1A1
SCHEMBL27670459 0.90 ALDH1A1 (0.36) ALDH1A1TSHRFGFR4
Acrylamide SCHEMBL29171645 0.88 ALDH1A1 (0.50) LMNAALOX15BLMPMP22ALDH1A1
Acetic Acid SCHEMBL7555401 0.86 FFAR3 (0.39) LMNAALDH1A1
Methacrylic Acid SCHEMBL10536704 0.80 ALDH1A1 (0.33) ALDH1A1TDP1
Acrylic Acid SCHEMBL5083639 0.78 ALDH1A1 (0.38) ALDH1A1
SCHEMBL2162008 0.78 ALDH1A1 (0.32) ALDH1A1
SCHEMBL28680465 0.78
SCHEMBL6943221 0.77 ALDH1A1 (0.31) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130129657-A1 SPRAYABLE COMPOSITION COMPRISING HIGH MOLECULAR WEIGHT CHARGED POLYMER ISP INVESTMENTS INC. (US) 2013-05-23 US claimed
EP-2555741-A1 SPRAYABLE COMPOSITION COMPRISING HIGH MOLECULAR WEIGHT CHARGED POLYMER ISP Investments Inc. (US) 2013-02-13 EP claimed
WO-2011126978-A1 SPRAYABLE COMPOSITION COMPRISING HIGH MOLECULAR WEIGHT CHARGED POLYMER ISP INVESTMENTS INC. (US) 2011-10-13 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130129657-A1 SPRAYABLE COMPOSITION COMPRISING HIGH MOLECULAR WEIGHT CHARGED POLYMER PARN, PARG, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 LMNA 4439/4885ALOX15 2882/4885BLM 1127/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.