Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 6/20 | 0.40 |
| ▸ | PARP2 | Q9UGN5 | 6/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 2/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17066447 | 0.75 | KMT2A (0.55) | KMT2ANPC1RAB9AMEN1CHRNB2 | |
| SCHEMBL26126783 | 0.74 | PARP1 (0.39) | PARP1PARP2KCNH2KMT2AMEN1 | |
| SCHEMBL8631458 | 0.73 | HRH3 (0.50) | TSHRALDH1A1HRH3 | |
| SCHEMBL2510973 | 0.70 | KMT2A (0.50) | KMT2ANPC1RAB9AMEN1CHRNB2 | |
| SCHEMBL29261428 | 0.69 | KMT2A (0.49) | KMT2ANPC1RAB9AMEN1CHRNB2 | |
| SCHEMBL27515414 | 0.69 | ME3 (0.50) | KMT2ANPC1RAB9ATSHRALDH1A1 | |
| SCHEMBL176857 | 0.69 | F2 (0.45) | KMT2AMEN1CHRNB2CHRNA5CHRNA7 | |
| SCHEMBL28495717 | 0.68 | HPGD (0.53) | KMT2ANPC1RAB9AMEN1CHRNB2 | |
| SCHEMBL1249246 | 0.68 | HPGD (0.53) | KMT2ANPC1RAB9AMEN1CHRNB2 | |
| SCHEMBL17066251 | 0.68 | HRH3 (0.45) | KCNH2NPC1TSHRHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023096915-A1 | MULTICYCLIC COMPOUNDS | SLAP PHARMACEUTICALS LLC (US) | 2023-06-01 | — | — | WO | disclosed |