Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23141140 | 0.78 | SPHK1 (0.59) | SPHK1 | |
| SCHEMBL3436860 | 0.78 | — | — | |
| SCHEMBL3436861 | 0.78 | — | — | |
| SCHEMBL6510225 | 0.78 | — | — | |
| SCHEMBL21464803 | 0.77 | SPHK1 (0.62) | SPHK1 | |
| SCHEMBL8131220 | 0.77 | PIK3CD (0.34) | SPHK1PIK3CD | |
| SCHEMBL10458440 | 0.77 | PIK3CD (0.34) | SPHK1PIK3CD | |
| SCHEMBL7758258 | 0.75 | CHRNB2 (0.34) | SPHK1CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL6270834 | 0.73 | HSD17B10 (0.56) | SPHK1 | |
| SCHEMBL18403007 | 0.73 | HTT (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023086383-A1 | SELECT KRAS G12C INHIBITORS AND USES THEREOF | 1200 PHARMA LLC (US) | 2023-05-19 | — | — | WO | disclosed |