Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | GFER | P55789 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.55 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | CASP1 | P29466 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | PLEC | Q15149 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11831264 | 0.89 | HTT (0.63) | HTTMAPTGFERHPGDNPC1 | |
| SCHEMBL25547420 | 0.87 | HTT (0.53) | HTTALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL21241028 | 0.86 | MAPT (0.64) | HTTALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL30301295 | 0.84 | HTT (0.62) | HTTALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL171575 | 0.84 | HTT (0.62) | HTTALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL8234606 | 0.84 | HTT (0.62) | HTTALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL28964160 | 0.84 | HTT (0.62) | HTTALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL5541171 | 0.84 | HTT (0.49) | HTTALDH1A1MAPTGFERHPGD | |
| SCHEMBL30687012 | 0.83 | GFER (0.54) | HTTALDH1A1MAPTMEN1KMT2A | |
| N-Benzyl-4-Methylaniline SCHEMBL171785 | 0.82 | HTT (1.00) | HTTALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023081967-A1 | COMPOUNDS AND USES THEREFOR | THE UNIVERSITY OF WESTERN AUSTRALIA (AU) | 2023-05-19 | — | — | WO | disclosed |