Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.64 |
| ▸ | HTT | P42858 | 2/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.64 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.49 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11831264 | 0.90 | HTT (0.63) | MAPTHTTCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL259701 | 0.90 | MAPT (0.65) | MAPTHTTCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL25547340 | 0.88 | MAPT (0.50) | MAPTHTTCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL13920564 | 0.88 | MAPT (0.55) | MAPTHTTCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL4951737 | 0.88 | MAPT (0.59) | MAPTHTTCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL25547404 | 0.86 | HTT (0.69) | MAPTHTTHPGDNPC1RAB9A | |
| SCHEMBL14294800 | 0.85 | MAPT (0.56) | MAPTHTTCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL20723944 | 0.83 | MAPT (0.58) | MAPTHTTCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL20997736 | 0.83 | INSR (0.55) | MAPTHTTCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL21086600 | 0.82 | MAPT (0.45) | MAPTHTTCYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019149260-A1 | PYRIDAZINOL COMPOUND, DERIVATIVE THEREOF, PREPARATION METHOD THEREFOR, HERBICIDAL COMPOSITION AND USE THEREOF | 青岛清原化合物有限公司 | 2019-08-08 | — | — | WO | disclosed |