Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | INPP5A | Q14642 | 2/20 | 0.40 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.31 |
| ▸ | ITPR3 | Q14573 | 3/20 | 0.30 |
| ▸ | ITPR2 | Q14571 | 1/20 | 0.30 |
| ▸ | ITPR1 | Q14643 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL685174 | 0.78 | INPP5A (0.44) | INPP5ASMPD1 | |
| SCHEMBL2238965 | 0.73 | — | — | |
| SCHEMBL10241703 | 0.73 | SMN1; SMN2 (0.44) | INPP5A | |
| SCHEMBL681678 | 0.73 | HRH3 (0.41) | INPP5A | |
| SCHEMBL13602505 | 0.73 | INPP5A (0.40) | INPP5A | |
| SCHEMBL24407723 | 0.73 | INPP5A (0.40) | INPP5ASMPD1ITPR3ITPR2ITPR1 | |
| SCHEMBL31470602 | 0.71 | INPP5A (0.41) | INPP5A | |
| SCHEMBL22479228 | 0.71 | INPP5A (0.41) | INPP5A | |
| SCHEMBL2149479 | 0.69 | INPP5A (0.52) | INPP5ASMPD1ITPR3ITPR2ITPR1 | |
| SCHEMBL2238021 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3787626-B1 | PHOSPHONAMIDATES THAT ARE BCL FAMILY ANTAGONISTS FOR USE IN CLINICAL MANAGEMENT OF CONDITIONS CAUSED OR MEDIATED BY SENESCENT CELLS AND FOR TREATING CANCER | UNITY BIOTECHNOLOGY INC (US) | 2023-06-07 | — | — | EP | disclosed |