Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 9/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.36 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1536419 | 0.81 | CYP1A2 (0.47) | L3MBTL1CYP1A2CYP2A6PDPK1ABL1 | |
| SCHEMBL30367774 | 0.80 | CYP1A2 (0.44) | L3MBTL1CYP1A2CYP2A6PDPK1 | |
| SCHEMBL22288174 | 0.77 | L3MBTL1 (0.56) | L3MBTL1MAPK1CYP1A2CYP2A6PDPK1 | |
| SCHEMBL3076096 | 0.77 | L3MBTL1 (0.51) | L3MBTL1CYP1A2CYP2A6PDPK1ABL1 | |
| SCHEMBL559117 | 0.77 | CDK2 (0.39) | MAPK1C5AR1KDM4EALDH1A1 | |
| SCHEMBL30452394 | 0.76 | L3MBTL1 (0.58) | L3MBTL1MAPK1CYP1A2CYP2A6PDPK1 | |
| SCHEMBL22288137 | 0.76 | L3MBTL1 (0.58) | L3MBTL1MAPK1CYP1A2CYP2A6PDPK1 | |
| SCHEMBL20623030 | 0.76 | L3MBTL1 (0.58) | L3MBTL1MAPK1CYP1A2CYP2A6PDPK1 | |
| SCHEMBL744363 | 0.75 | PDE10A (0.50) | PDE10AMAPK1TRPV3KDM4EALDH1A1 | |
| SCHEMBL30408061 | 0.75 | PDE10A (0.50) | PDE10AMAPK1TRPV3KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023081666-A1 | COMPOUNDS AS CCR2 MODULATORS | ARIA PHARMACEUTICALS, INC. (US) | 2023-05-11 | — | — | WO | disclosed |