Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29937218 | 0.78 | NUDT1 (0.33) | NUDT1RPS6KA2 | |
| SCHEMBL29344239 | 0.78 | NUDT1 (0.33) | NUDT1RPS6KA2 | |
| SCHEMBL24785873 | 0.77 | NUDT1 (0.34) | NUDT1RPS6KA2 | |
| SCHEMBL29301859 | 0.77 | NUDT1 (0.34) | NUDT1RPS6KA2 | |
| SCHEMBL288526 | 0.74 | NUDT1 (0.41) | NUDT1RPS6KA2 | |
| SCHEMBL18614436 | 0.73 | PIK3CA (0.33) | NUDT1 | |
| SCHEMBL29301858 | 0.73 | NUDT1 (0.43) | NUDT1RPS6KA2 | |
| SCHEMBL288312 | 0.70 | NUDT1 (0.41) | NUDT1RPS6KA2 | |
| SCHEMBL18645375 | 0.70 | NUDT1 (0.68) | NUDT1RPS6KA2 | |
| SCHEMBL29297683 | 0.70 | NUDT1 (0.34) | NUDT1RPS6KA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023097227-A1 | SMALL MOLECULE INHIBITORS OF KRAS MUTATED PROTEINS | MERCK SHARP & DOHME LLC (US) | 2023-06-01 | — | — | WO | disclosed |