Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 6/20 | 0.57 |
| ▸ | SLC6A5 | Q9Y345 | 3/20 | 0.56 |
| ▸ | CNR1 | P21554 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.51 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25549652 | 0.98 | EPHX2 (0.61) | EPHX2SLC6A5CNR1KDM4ELPAR1 | |
| SCHEMBL25549709 | 0.98 | EPHX2 (0.61) | EPHX2SLC6A5CNR1KDM4ELPAR1 | |
| SCHEMBL25549752 | 0.94 | CNR1 (0.63) | EPHX2CNR1KDM4EALDH1A1HPGD | |
| SCHEMBL25549812 | 0.93 | CNR1 (0.64) | SLC6A5CNR1KDM4EALDH1A1HPGD | |
| SCHEMBL25542893 | 0.90 | NOD1 (0.58) | EPHX2LPAR1 | |
| SCHEMBL25542908 | 0.90 | NOD1 (0.58) | EPHX2LPAR1 | |
| SCHEMBL25542862 | 0.90 | NOD1 (0.58) | EPHX2LPAR1 | |
| SCHEMBL16264552 | 0.90 | NOD1 (0.58) | EPHX2LPAR1 | |
| SCHEMBL19308433 | 0.90 | NOD1 (0.58) | EPHX2LPAR1 | |
| SCHEMBL25542898 | 0.90 | NOD1 (0.58) | EPHX2LPAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230158150-A1 | COMPOUND COMPRISING A NUCLEIC ACID AND A HALF-LIFE EXTENSION MOTIF | NOVARTIS AG (CH) | 2023-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230158150-A1 | COMPOUND COMPRISING A NUCLEIC ACID AND A HALF-LIFE EXTENSION MOTIF | NSUN2, NSUN3, POLM | EPHX2 3717/4885SLC6A5 4282/4885CNR1 4709/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.